BACKGROUND Health-related quality of life (HRQoL) is affected by numerous variables including depression and anxiety. However, these associations have not yet been described among patients with systemic lupus erythematosus (SLE) and the impact of SLE-related clinical variables remains unknown. OBJECTIVES In this cross-sectional study, the prevalence of depression and anxiety among Iranian pat...

BACKGROUND The relationship of inflammatory cytokines with anxiety and depression has been reported, but their role in diabetic patients has not been fully elucidated. OBJECTIVE We examined whether an association between prevalence of anxiety and depression in Omani type-2 diabetic patients (n=30) and the levels of inflammatory markers such as IL-1ß, TNF-α, IFN-γ and C-reactive protein (CRP) ...

Depressive and anxiety disorders are frequently observed in patients with Systemic Lupus Erythematosus (SLE). However, the underlying mechanisms are still unknown. We conducted this survey to understand the prevalence of depression and anxiety in SLE patients without major neuropsychiatric manifestations (non-NPSLE) and to explore the relationship between emotional disorders, symptoms, autoanti...

Alcohol addiction is a worldwide problem. It has mainly two components: dependence and withdrawal. Characteristic properties of most anti-addictive compounds include anti-anxiety, anticonvulsant, antidepressant, and nootropic actions. Shankhpushpi (Convolvulus pluricaulis. Convolvulaceae), known ethnopharmacologically as brain tonic, possess all the properties mentioned above. Here, we screen s...

Neuropsychiatric lupus (NPSLE), a manifestation of the autoimmune disease systemic erythematosus (SLE), is characterized by psychiatric symptoms including anxiety and depression upregulated autoantibodies. The B6.Nba2 spontaneous mouse model develops SLE, but has not previously been tested for NPSLE. We investigated NPSLE phenotype in male female mice (n = 12 each) age- sex-matched B6 controls ...

The Present study was aimed to evaluate the therapeutic effectiveness of 1, 5-benzothiazapine derivative in central nervous diseases. 1,5Benzothiazipines are the seven–membered heterocyclic ring systems which are reported for their behavioral activities. In the current research, we have investigated the effect of 1,5-benzothiazine derivative for its anti-anxiety, antidepressant and anti-catalep...

Superstitions and rituals are commonplace in sports and range from simple activities such as each player touching a special inanimate object before entering the field of play to more extreme behaviours such as not washing a uniform or wearing the same underwear during a winning streak. These practices are relatively harmless and may reduce precompetition anxiety, but a concerning ritual that ha...

Anxiety is one of the most common symptoms of mental disorders, significantly affecting work function and interpersonal relationships. Its characteristics include a set of cognitive, physical, emotional and behavioral-symptoms. Some of these symptoms are: feeling empty heart, shortness of breath, palpitations, flushing, excessive sweating, numbness, dizziness and shaking hands. Given the high p...