A 6-year-old boy presented with epilepsia partialis continua 6 months after diagnosis of type 1 diabetes. Anti-glutamic acid decarboxylase 65 antibodies were found in his serum and cerebrospinal fluid. Anti-epileptic agents did not improve his seizures. High-dose steroids, plasmapheresis, and intravenous immunoglobulin resulted in decreased anti-glutamic acid decarboxylase 65 antibody levels an...

Background: Epilepsy is a chronic disease characterized by the occurrence of recurrent non provoked epileptic seizures. This condition affects quality life those affected as well their caregivers’ not only itself but also because comorbidity. It requires daily care and continuous use anti seizure medication at specific times day.

A series of experiments was carried out testing the hypothesis that the septal region decreases the hippocampal susceptibility to hyperexcitability states through theta rhythm generation. Medial septal neurons were simultaneously recorded with hippocampal field potentials to investigate the septo-hippocampal function in the pilocarpine model of chronic epilepsy. The theta rhythm from chronicall...

Introduction, Epilepsy: basic mechanisms, Epilepsy: aetiology, Epidemiology of epilepsy, Classification of epilepsy. Management of epilepsy, Treatment, Management of the chronic patient, Anti-epileptic drugs, Counselling and social support for people with epilepsy, Surgical treatment of epilepsy, Other non-medical treatments for epilepsy, Women with epilepsy, Intelligence, learning, cognition a...

First epileptic seizure is a common reason for attending the emergency department. Its management is focused on diagnosis of the episode and on identification and treatment of the underlying cause. Occasionally, anti-epileptic treatment will be required. However, when the seizure is prolonged - a condition known as status epilepticus - it becomes a life-threatening process and requires immediat...