Peganum harmala (Zygophyllaceae) is an intriguing herb with a long history of medicinal use. Antifungal activity of P. harmala seed extract against certain fungal species was investigated in vitro. Antifungal activity of the extract of P. harmala seeds was investigated against several fungal species using in vitro agar dilution technique. The fungal species included: Microsporum canis, Microspo...

Peganum harmala (Zygophyllaceae) is an intriguing herb with a long history of medicinal use. Antifungal activity of P. harmala seed extract against certain fungal species was investigated in vitro. Antifungal activity of the extract of P. harmala seeds was investigated against several fungal species using in vitro agar dilution technique. The fungal species included: Microsporum canis, Microspo...

Fungal extracts are extensively used as nutritional supplements in Far-Eastern Asia. In this study, we aimed to evaluate the anti-cancer activities of some different fungal species against different cancer cell lines. The water or ethanol extracts of Fomitopsis pinicola (F. pinicola), Ganoderma sinense, Fomitopsis officinalis, Polyporus melanopus, and Taiwanofungus camphorates were used to eval...

The microbial contamination in food packaging has been a major concern that has paved the way to search for novel, natural anti-microbial agents, such as modified α-mangostin. In the present study, twelve synthetic analogs were obtained through semi-synthetic modification of α-mangostin by Ritter reaction, reduction by palladium-carbon (Pd-C), alkylation, and acetylation. The evaluation of the ...

Candida albicans is the most common cause of oral mycoses. The aim of the present study was to investigate in vitro the susceptibility of C. albicans to mouthwashes, in terms of growth, survival and biofilm formation. Candida albicans, laboratory strain SC5314, and 7 commercial mouthwashes were employed: 3 with 0.2% chlorhexidine digluconate; 1 with 0.06% chlorhexidine digluconate and 250 ppm F...

Abroma augusta (L.) L. f. has been used as traditional medicine by tribal women in India, Bangladesh forms ancient times. Ayurvedic medicine, derived from herbal plants is to reduce the gamble effects of synthetic drugs. In homeopathy, it using successfully for a long period. Major Phytochemicals such as, Taraxerol, Friedelin, β-Sitosterol, α-Amyrin, Lupeol, Octacosanol, have potentialities con...

BACKGROUND Fungal corneal ulcer is one of the major causes of visual impairment worldwide. Treatment of fungal corneal ulcer mainly depends on anti-fungal agents. In the current study, we developed an integrated combination therapy of cryotherapy and anti-fungal agents to facilitate effective treatment of fungal corneal ulcer. METHODS Rabbit models of cornea infection were established using a...

A series of novel 1, 2, 4-oxadiazole derivatives were synthesized and evaluated for invitro antibacterial and antifungal activity. All the compounds tested against bacteria showed comparable or less antibacterial activities than the reference drug. Differences in their activity depend on the substitution of different groups. More specifically, best antibacterial activity among synthetic analogu...