epilepsy is a neurological disease of the central nervous system. it is estimated that about 50-70 million people worldwide suffer from this chronic disorder and 20 to 30% are resistant to conventional anti-epileptic drugs. in the epilepsy therapeutic arena, there is real need for developing novel antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the dis...

OBJECTIVE Dietary changes play major risk roles in oxidative stress and cardiovascular disease and modulate normal metabolic function. The present study was designed to investigate the ameliorative potential of different extracts of Hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action. MATERIALS AND METHODS Male wistar rats were divided into ...

Dyslipidemia is one of the most common complications in diabetes mellitus, which increases risk of premature atherosclerosis. Drugs having antihyperlipidemic activity in addition to their hypoglycemic effect in diabetes may be suitable anti-atherosclerotic agents in diabetic patients. The present study was aimed to investigate the anti-atherosclerotic activity of an aqueous extract of Withania ...

People believe that sumac is used as reducing fat. In the present study, the hypolipidemic effect of sumac fruits was compared with lovastatin in patients suffered hypercholesterolemia. In a randomized double-blinded-controlled trial, 172 patients diagnosed as hypercholesterolemia (high LDL level) and indicated for lipid-lowering schedules were randomly allocated to receive lovastatin (20 mg/da...

diabetes is a common metabolic disease in the world that has many adverse effects. olibanum gum resin (from trees of the genus boswellia) has traditionally been used in the treatment of various diseases such as diabetes. the aim of this study was the comparison of olibanum gum resin effect with placebo on the treatment of type 2 diabetes. inclusion criteria was diabetic patients with fasting bl...

Epilepsy is a neurological disease of the central nervous system. It is estimated that about 50-70 million people worldwide suffer from this chronic disorder and 20 to 30% are resistant to conventional anti-epileptic drugs. In the epilepsy therapeutic arena, there is real need for developing novel antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the dis...

Cardio vascular diseases are leading cause of death in both industrialized and developing nations. Disorders of lipid metabolism, following oxidative stress are the prime risk factors for initiation and progression of these diseases[1]. The current anti-hyperlipidemic therapy includes principally statins and fibrates, the former corrects the altered blood lipid profile by inhibiting the bio-syn...