Emergence of resistance by bacterial and fungal stains towards existing antimicrobial agents is one of the major problem as well as motivation to synthesize a new class of antimicrobial agents possessing potent activity compared to commonly used therapy. Coumarin is the heterocyclic compound formed from benzene and pyrone ring containing oxygen and its derivatives are of wide awareness because ...

Objectives: To investigate the alterations in the oxidant-antioxidant balance in patients with acute ischaemic stroke, and to locate any correlation between oxidant/antioxidant parameters and the National Institute of Health Stroke Scale. Methods: The case-control study was conducted at the Neurology Department of Dicle University Medical Faculty, Diyarbakir, Turkey, from June 2010 to June 2011...

In this study a cobalt(II) complex of quercetin was synthetized in the solid state with general formula Co(C15H9O7)2∙2H2O. The FT-IR, elemental analysis, and UV/Vis methods were used to composition water solution. anti-/pro-oxidant activity Co(II) studied by means spectrophotometric DPPH (2,2-diphenyl-1-picrylhydrazyl), FRAP (ferric reducing antioxidant activity) Trolox oxidation assays. cytoto...

Pink oyster mushroom (Pleurotus djamor) owns a pleasant colour, good sensory attributes, high nutritional value, anti-oxidant, anti-microbial and medicinal properties. Cultivation of different types has been accepted as short-term income generating avenue under crop production for livelihood the farmers. The present study was carried out to assess quality, anti-oxidant activities economic benef...

PURPOSE Oxidative damage plays an important role in atherosclerosis development. Statin drugs have anti-oxidant properties, but the clinical value of their antioxidant properties remains unclear. In this study, our aims were: (1) to assess the anti-oxidant effects of statins in patients with coronary artery disease (CAD) using a newly developed valid measure of total oxidant and anti-oxidant ca...

Rosemary extracts containing the phenolic diterpenes carnosic acid and its derivative carnosol are approved food additives used in an increasingly wide range of products to enhance shelf-life, thanks to their high anti-oxidant activity. We describe here the elucidation of the complete biosynthetic pathway of carnosic acid and its reconstitution in yeast cells. Cytochrome P450 oxygenases (CYP76A...

Objective(s): Noise-induced hearing loss is one of the most common occupational diseases in industrialized countries and can be affected by various environmental and genetic factors. This study was designed to examine the effect of myricetin in preventing this disorder.Materials and Methods: Twenty-one Wistar rats were randomly divided i...