OBJECTIVE To evaluate the role of intrapleural streptokinase in the management of complicated parapneumonic effusions in children. DESIGN Prospective comparative study. SETTING Cheng Kung University Hospital, a tertiary medical center in Tainan, Taiwan. PATIENTS AND METHODS We enrolled as our prospective study group 20 consecutive children with complicated parapneumonic effusions who rece...

BACKGROUND AND PURPOSE We used 99mTc-hexamethylpropyleneamine oxime single-photon emission computed tomography (SPECT) to study cerebral perfusion in patients treated with streptokinase for acute ischemic stroke in an open and prospective study. Our primary aims were (1) to compare the extent of reperfusion between patients who had received thrombolytic therapy and a control group studied durin...

.. Several strains of beta-hemolytic Streptococci produce streptokinase enzyme that can bind and activate human plasminogen to plasmin. Streptokinase degrades the fibrin lump by its explicit lysine joining site and so it is applied as a remedy in thrombolytic therapy. The purpose of the study was to subject wild strain of Streptococcus equisimilis to strain development technique, using random m...

The activation of human plasminogen by streptokinase has been the subject of extensive investigation (4-8). There appears to be general agreement that at least two enzymatic activities are demonstrable in streptokinase-plasminogen reaction mixtures. One is the proteolytic enzyme human plasmin, characterized in part by its ability to hydrolyze lysine and arginine esters and protein substrates su...

The present study was performed to identify stress-induced putative virulence proteins of Streptococcus suis. For this, protein expression patterns of streptococci grown at 32, 37, and 42 degrees C were compared by one- and two-dimensional gel electrophoresis. Temperature shifts from 32 and 37 to 42 degrees C induced expression of two cell wall-associated proteins with apparent molecular masses...

Peak serum C-reactive protein concentrations were measured in 146 patients randomized to receive streptokinase, alteplase, or a combination of streptokinase and alteplase in the GUSTO-I trial. Those receiving alteplase treatment had lower values than those receiving streptokinase or the combination treatment. Irrespective of treatment, complete reperfusion of the infarct-related artery (TIMI gr...

Failure of hemostasis and the formation blood clots in arteries are main reasons that provoke onset cardiovascular diseases (CVDs) such as myocardial infarction ischemic stroke. Cardiovascular have become primary cause deaths disabilities across globe. Therefore, this problem needs to be addressed with urgency. The disintegration requires fibrinolytic agents, which involved thrombolysis. Strept...

BACKGROUND Streptokinase is a routinely used thrombolytic agent that is immunogenic and relatively inefficient toward platelet-rich thrombus, whereas staphylokinase is a poorly studied fibrinolytic agent. Here, the comparative immunogenicity and thrombolytic properties toward arterial platelet-rich thrombus and venous whole blood clots of streptokinase and recombinant staphylokinase were studie...

Rationale: The term “fragmentation of the QRS complex” denotes existence high-frequency potentials (spikes) in QRS-complex. It is either a marker for cardiac structural diseases inducing biventricular hypertrophy or any condition interfering with normally homogeneous depolarization status inside myocardium. An associated right ventricular infarction inferior maybe carry risk impact and serious ...