objective in this study, we investigated the changes of the serum levels of thyroidhormones including thyroxine (t4), triiodothyronine (t3), t3 resin uptake andthyroid stimulating hormone (tsh) in epileptic children during treatment withanti-epileptic drugs (aeds) including carbamazepine (cbz), primidone (prm),phenobarbital and valproic acid (vpa). materials and methods this study consisted of ...

the occurrence of neonatal seizures may be the first and perhaps, the only clinical sign of a central nervous system (cns) disorder in the newborn infant. identifying the etiology for the neonatal seizures is/critical to prognosis and treatment. the most common etiology for neonatal seizures is hypoxic-ischemic encephalopathy. seizures may indicate the presence of a potentially treatable etiolo...

how to cite this article: ghofrani m. approach to the first unprovoked seizure- part i. iran j child neurol. 2013 summer; 7(3): 1- 5.   the approach to a child who has experienced a first unprovoked generalized tonic-clonic seizure is challenging and at the same time controversial. how to establish the diagnosis, ways and means of investigation and whether treatment is appropriate, are differen...

how to cite this article: ghofrani m. approach to the first unprovoked seizure- part ii. iran j child neurol. 2013 autumn; 7(4):1-5. abstract the approach to a child who has experienced a first unprovoked generalized tonic-clonic seizure is challenging and at the same time controversial. how to establish the diagnosis, ways and means of investigation and whether treatment is appropriate, are di...

background epilepsy is a chronic neurological disease with the prevalence of around one percent. despite the introductions of several anti-epileptic drugs, around 1/3 of epileptic patients are resistant to the anti-epileptic medications. objectives considering the evidence regarding the anti-oxidant action of vitamin e and its beneficiary effect in the treatment of epilepsy, we investigated the...

Valproic acid is widely used as an anti-epileptic globally. Anti-epileptic action is mediated by Gamma Amino Butyric Acid (GABA) receptors. In past and recently, several other clinical outcomes have been proposed by various studies. These under-reported clinical actions apart from anti-epileptic activity are mediated by various intracellular and extracellular pathways. Several mechanisms like H...

how to cite this article: allahdin s, khademvatan s, rafiei a, momen aa, rafiei r. frequency of toxoplasma and toxocara sp. antibodies in epileptic patients, in south western iran. iran j child neurol. autumn 2015;9(4):32-40. abstract objective epilepsy is a disorder of the brain characterized by an enduring predisposition to generate seizures. infectious agents are mentioned in its etiology. w...

oxidative stress has been suggested as a consequence and as a cause of epileptic seizures. researches indicate achillea wilhelmsii (a.wilhelmsii) has anti-oxidant and anti-spasmic effects on central nervous system. this plant grows in most part of iran. an iranian research that done in 2013 showed that the hydroalcoholic extract of achillea wilhelmsii possesses an antioxidant effect in the brai...