Antibiotic use is the main driver in the emergence of antibiotic resistance. Another unexplored possibility is that resistance evolves coincidentally in response to other selective pressures. We show that selection in the absence of antibiotics can coselect for decreased susceptibility to several antibiotics. Thus, genetic adaptation of bacteria to natural environments may drive resistance evol...

To promote heightened vigilance concerning antibiotic agents in Canadian hospitals, Accreditation Canada has implemented antibiotic stewardship as a required organizational practice.1 Antibiotic stewardship is the process of ensuring that only necessary and appropriate antibiotic agents are used and that their use is appropriate for each individual patient. It involves optimizing all steps of a...

objective(s) amongst the various antibiotic resistant elements in vibrio. cholerae, sxt constin (sxt-c) is important. we were going to design a quick method for determination of antibiotic resistance gene pattern in sxt-c. materials and methods ninety four v. cholerae o1el tor isolates were used in this study. antibiotic susceptibility testing, multiplex pcr amplification of sxt-c containing df...

abstract background: acute respiratory infections (ari) are the main cause for antibiotic (ab) use in all age groups specially the first two years of life. the local information about the pattern of ab prescription in ari is a necessary part for any program which aims logical use of ab. the current study was designed to find the frequency and types of ab administration for ari in young children...

one of the great challenges in the treatment of infectious diseases is the resistance of pathogenic bacteria against antibiotics, and antibiotic resistance to shigella is broadly observed in different parts of the world. the object of this study was to determine shigella antibiotic resistance pattern against the antibiotics such as ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, chloram...

background and objectives: the appearance of antibiotic resistance in streptococcus pneumoniae has raised a global concern over the past three decades. this study was conducted to determine the antimicrobial susceptibility of s. pneumoniae isolated from patients in children´s medical center (cmc) hospital during 2001 to 2011. materials and methods: during the 11 years period, a total of 194 s. ...

conclusions according to the results, six strains were resistant to six or seven antibiotics and all strains were at least resistant to two antibiotics. however, for each of these resistant bacteria one bacteriophage was isolated from environmental samples, which showed the effectiveness of bacteriophages to remove clinically resistant e. coli strains. effective phages in vitro showed effective...

introduction: diseases of the dental pulp and periapical tissues are chiefly caused by microorganisms. antibiotics are used in some endodontic cases; however, successful cases can predominantly be achieved by mechanical and chemical cleaning of the canal or surgical intervention. materials & methods: the aim of this study was to determine the knowledge of general dental practitioners (gdps) in ...

Antibiotic-Resistant Pattern and Multiple Antibiotic Index of Multidrug-Resistant Staphylococcus aureus from Wound Infection Patients in a Tertiary Institution South Eastern Nigeria

The Core Elements of Outpatient Antibiotic Stewardship provides a framework for antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic treatment. This report augments existing guidance for other clinical settings. In 2014 and 2015, respectively, CDC released the Core Elements of Hospital Antibiotic Stewardship Programs and the Core Elements of Antibiot...