Colistin relates to the polymyxin group of antibiotics. This antibiotic is still used to destroy gram-negative bacteria as a last resort. However, resistance to this antibiotic has been reported and is appearing day by day. Not much information is available on the exact mechanisms of resistance to this antibiotic. Also, not enough information about pharmacokinetics and pharmacodynamics is avail...

antimicrobial resistance in pathogens not only in hospitals but also in the community has become an important public health problem. the aim of this study was to determine the antimicrobial resistance patterns of predominant pathogens from hospitalized and outpatients in a university hospital in tehran, iran. a total of 820 samples of common gram-negative and gram-positive bacteria were collect...

Introduction: Resistance of pathogenic organisms to countenance antibiotics has become a worldwide problem with serious consequences on the treatment of infectious diseases. The aim of this study was to evaluate antibiotic resistance and also the detection of transferred antibiotic resistance by plasmid in clinical Proteus isolates. Materials and methods: A total of 250 urine samples were ...

Background: Methicillin-Resistant Staphylococcus aureus (MRSA) has been an important cause of bone infection since the 1940s. Current guidelines recommend targeted antibiotic use for osteomyelitis treatment informed by microbial sensitivity patterns. However, in settings without microbiology facilities, empirical antibiotic use is common. Unrecognized antibiotic resistance potentiates persisten...

The present study was done to evaluate the presence of antibiotic resistance genes in Lactococcus garvieae isolated from cultured rainbow trout, West Iran.The isolates were examined for antimicrobial resistance using disc diffusion method. Of the 24 strains tested, 21 were resistant to ampicillin (87.5%), 9 to erythromycin (37.5%) and 19 to tetracycline (79.1%). Fourteen strains were resistant ...

The worldwide epidemic of antibiotic resistance is in danger of ending the golden age of antibiotic therapy. Resistance impacts on all areas of medicine, and is making successful empirical therapy much more difficult to achieve. Antibiotic choices are often severely restricted, and the pipeline of new antibiotics is almost dry. Resistance cannot be prevented, but its development and spread can ...

background :   ampc β-lactamases are important cephalosporinases chromosomally encoded in many of enterobacteriaceae and a few other organisms where they mediate resistance to cephalothin, cefazolin, cefoxitin and penicillins. the six different families of plasmid-mediated ampc β-lactamases have been described, but no phenotypic test can discriminate among them. ampc multiplex pcr has been succ...

background and objectives: group b streptococci (gbs) is a major cause of neonatal and maternal infections. the aim of this study was to determine the serotype distribution and antibiotic resistance profile of gbs strains isolated from pregnant women in ardabil. materials and methods: antibiotic resistance of 56 gbs isolates was investigated using e-test strips and disk-diffusion method. seroty...