The anticonvulsant pregabalin promotes neural regeneration in a mouse model of spinal cord injury (SCI). We have also previously observed that anticonvulsants improve motor outcomes following human SCI. The present study examined the optimal timing and type of anticonvulsants administered in a large, prospective, multi-center, cohort study in acute SCI. Mixed-effects regression techniques were ...

background: cicer arietinum (chickpea) is one of the most important harvests in the world with high nutritional value. lack of essential oils in the seeds of chickpea is an advantage in search for drug-like molecules with less toxicity. we evaluated anticonvulsant effect of c. arietinum in common animal models of epilepsy. methods: dichloromethane extract was obtained from c. arietinum seeds by...

PURPOSE This study was to evaluate the relationship of 25(OH)D3 levels with anticonvulsant use and other possible factors in epileptic children and adolescents. MATERIALS AND METHODS We studied 143 patients with epilepsy (90 boys, 53 girls; 11.21±4.49 years), who had been treated with anticonvulsants for more than 1 year. Patients who had taken multiple vitamins before the blood test and thos...