Objective of the study was to assess the antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats. Methods: The antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats was assessed using Alloxan βcytotoxin induced chemical diabetes in a wide variety of wister albino rats. Result: The polyherbal formulation contain the following plants leaves ...

The control over diabetes mellitus depends upon the availability of insulin. Various efforts have been made in the recent past to control / check it. There is an increasing demand to use the natural antidiabetic agents. The literature pertaining to antidiabetic herbs is scattered. The present article is a conglomeration of available indigenous literature. It gives an additional information of l...

Diabetes mellitus remains a burden worldwide in spite of the availability of numerous antidiabetic drugs. Honey is a natural substance produced by bees from nectar. Several evidence-based health benefits have been ascribed to honey in the recent years. In this review article, we highlight findings which demonstrate the beneficial or potential effects of honey in the gastrointestinal tract (GIT)...

Present study was aimed to isolate and evaluate the antidiabetic activity of phytoconstituents from fruit rinds of Punica granatum. With the above objectives Valoneic acid dilactone (VAD) was isolated from methanolic fruit rind extracts of Punica granatum (MEPG) and confirmed by (1)H-NMR, (13)C-NMR, and mass spectral data. Antidiabetic activity was evaluated by Aldose reductase, α-amylase and P...

Although antidiabetic agents have been developed to target one or more of the core defects of type 2 diabetes mellitus (T2DM), many patients do not achieve glycemic goals. Inhibition of the sodium-glucose cotransporter 2 (SGLT2) induces glycosuria, reduces glucose toxicity and improves insulin sensitivity and β-cell function. As the mechanism of action of SGLT2 inhibitors is different from othe...

The root of Combretum dolichopetalum (Combreatacea) is used in ethnomedicine for the management of diabetes mellitus. Though some compounds have been isolated from it, the antidiabetic principles have not been identified. The present study was designed to evaluate the chemical constituents from the root of C. dolichopetalum with a view to identifying the antidiabetic principles. The constituent...