Due to the presence of polyphenols and phthalides in Kelussia odoratissima Mozzaf (Umbelliferae; K. odoratissima hereafter), this medicinal plant might be a robust in-feed additive to modulate lipid peroxidation in meat-type chickens. The present study evaluates antioxidative, antihyperlipidemic, and growth-promoting effects of K. odoratissima in meat-type chickens. In a 37-day trial (5-42 days...

A series of antihyperlipidemic analogs of bis[2-(acylamino)phenyl]disulfides, 2-(acylamino) benzenethiols and S-[2(acylamino)phenyl] alkanethioates has been subjected to quantitative structure activity relationship analysis. They show that the cholesteryl ester transfer protein inhibitors as determined in the human are having significant correlation with steric (Principle moment of inertia of X...

In the field of medicinal chemistry, Quinazolinone is a heterocyclic compound having unique place which has medicinal uses as Anticancer, antihypertensive, antihyperlipidemic, antitubercular, CNS depressant, antioxidant, analgesic, antibacterial, anti-inflammatory and antimalarial activity. Quinazolinone based drugs have broadened scope in the field of medicine and Research. Some quinazolinone ...

Dear Editor, Seven species have been reported in the genus Dorema, family Umbelliferae, in the flora of Iran, among which two are endemic: D. aucheri Boiss. and D. ammoniacum D. Don. 1 In Iranian traditional medicine, Dorema aucheri has been employed as stimulant, nervonic, antispasmodic, bronchodilator, expectorant, kidney stone repellent, emmenagogue and analgesic for visceral pain. This plan...

Six new caryophyllene-based sesquiterpenoids named punctaporonins H-M (1-6), together with punctaporonin B (7) and humulane (8) were isolated from the fermentation broth of the sponge-derived fungus Hansfordia sinuosae. Their structures were determined by the extensive HRESIMS and NMR spectroscopic analysis, including the X-ray crystallographic data for the assignment of the absolute configurat...

Background Mortality rate is increasing due to cardiovascular problems throughout the world. These cardiac problems are directly associated with dyslipidemia. Aim The aim of this study was to evaluate the antihyperlipidemic effect of aqueous extract and methanol extract of Trachyspermum ammi at 1 g/kg, 3 g/kg, and 5 g/kg dose levels in rats. Materials and Methods For this purpose, 45 male a...