background and objectives: cholera is an endemic diarrheal disease in iran, caused by vibrio cholerae . the epidemiology, transmission route, environmental determinants and antimicrobial resistant pattern of cholera have been changed during recent years. in this study the epidemiology and antimicrobial resistance of cholera in iran during 2013 outbreak was investigated. materials and methods: a...

results amongst 938 stool samples, 36 were shigella spp. s. sonnei (61.1%, n = 22), which was the most common, followed by s. flexneri (27.8%, n = 10), s. boydii (8.3%, n = 3), and s. dysenteriae (2.8%, n = 1). furthermore, most shigella isolates showed resistance to amoxicillin (83.3%), tetracycline (61.1%), and co-trimoxazole (83.3%). no resistance was found against ciprofloxacin and imipenem...

background scrophularia striata (scrophulariaceae family) is an herbaceous plant that is traditionally used for treatment of microbial infections. objectives antimicrobial and antioxidant activity of different extracts (methanolic, ethanolic, aqueous and ethyl acetate) from s. striata aerial parts was evaluated. materials and methods the antimicrobial activity of different extracts from s. stri...

b ackgro un d : the antimicrobial activity of silver nanoparticles has been investigated in medical fields in recent years, but there are few studies regarding its effect on oral microorganisms. the aim of the present study was to evaluate the in vitro antimicrobial and toxicity properties of nanosilver against two dental plaque microorganisms  and human gingival fibroblast (hgf) cell line. me ...

background and objective: pigment production by microorganisms is important due to more rapid growth, higher efficiency, easier extraction, and antimicrobial effects compared to other methods. the aim of the present study is to isolate and identify antibiotic pigment-producing actinomycetes from the soil of the persian gulf and to evaluate the antibiotic activity of their pigments in the second...

i ntroduction: calcium hydroxide (ch) is one of the most common intracanal medications. corticosteroids (cs) are used in endodontics because of their anti-inflammatory activity. this study aimed to evaluate the antimicrobial effect of ch+betamethasone and ch+saline against enterococcus faecalis ( e. faecalis ) using agar diffusion test and measuring the microbial zone of inhibition (zoi). metho...

The rise of antimicrobial resistance (AMR) is a severe global health problem. Tackling this problem requires the prudent prescribing of antimicrobials. This is promoted through Antimicrobial Stewardship Programs (ASPs). In this position paper we describe i) how a socio-technical multidisciplinary approach (based on the CeHRes Roadmap) can be applied in the development and implementation of Anti...

Total polyphenols content and a partial phenolics composition from pulp and peel of organically and conventionally produced Malus domestica, Annurca were investigated. Furthermore, the antimicrobial effect of these compounds against useful and pathogen microorganism was examined. Finally, their mutagenic activities were evaluated. Organically grown apples showed a greater content of polyphenols...

Infections and infectious diseases are considered a major challenge to human health in healthcare units worldwide. This opinion paper was initiated by EU COST Action network AMiCI (AntiMicrobial Coating Innovations) and focuses on scientific information essential for weighing the risks and benefits of antimicrobial surfaces in healthcare settings. Particular attention is drawn on nanomaterial-b...

The effectiveness of antimicrobial compounds can be easily screened, however their mechanism of action is much more difficult to determine. Many compounds act by compromising the mechanical integrity of the bacterial cell envelope, and our study introduces an AFM-based creep deformation technique to evaluate changes in the time-dependent mechanical properties of Pseudomonas aeruginosa PAO1 bact...