substituted schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. on cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds ...

objectives: evaluation of therapeutic effects of carum copticum (c. copticum) has been the subject of several studies in recent years. thymol the major component of c. copticum is a widely known anti-microbial agent. in this study, the antibacterial and anti viral activities of essential oil of c. copticum fruit were determined. materials and methods: essential oil of c. copticum was analyzed b...

substituted 1, 2, 4- triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. these triazoles were used for preparation of different derivatives by two different schemes. in the first scheme the mannich bases were prepared from 5- marcapto-s triazole quinazolines. the 5-marcato-s-tr...

background: anti-microbial agents have been used as a chemotherapeutic agent to improve oral health. this in vitro study was carried out to determine antimicrobial efficacy of different toothpastes and mouthrinses against the oral pathogens.     methods: a total of five toothpastes and five mouthrinses were tested for their antimicrobial activity against three oral pathogens namely, streptococc...

the in vitro antioxidant and antimicrobial activities of the essential oil and methanolic extract of achillea sieheana staf. (asteraceae) were investigated in this study. the chemical composition of the essential oil isolated by hydro-distillation from the aerial parts of a. sieheana was analyzed by gc–ms. camphor (43.36%), artemisia ketone (25.95%), 1.8-cineole (6.29%) and camphene (4.77%) wer...

background: although various surface disinfectants have been introduced, most of them are toxic. the use of natural antimicrobial agent e.g. phytol, extracted from leptadenia pyrotechnica is a new strategy. the aim of this study was to evaluate the antimicrobial activity, toxicity, and stability of phytol. methods: the serial concentrations of phytol were prepared, and separately incubated with...

the antimicrobial activity of methanolic extracts from different parts of 11 indigenous wild plantspecies used in traditional medicines of iran were tested against nine species of microorganisms: escherichiacoli, staphylococcus aureus, staphylococcus epidermis, pseudomonas aeruginosa, klebsiella pneumoniae,salmonella typhi, bacillus subtilis, aspergillus niger and candida albicans. the antimicr...

substituted schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. on cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds ...

a series of n-substituted-2,4-thiazolidinedione derivatives (tzds) were prepared via n-alkylation of 2,4-tzd at position 3 using substituted benzyl halides. synthesized n-substituted-2,4-tzd was then substituted at position 5 with substituted aromatic aldehyde according to knoevenagel condensation method. structures of the compounds were elucidated using various spectral techniques viz. ir, 1hn...

objective(s): mindium laevigatum is an endemic plant of iran and turkey and is widely used as blood purifier, antiasthma and antidyspnea in traditional medicine. chemical composition of volatile materials of the plant and its antioxidant, antimicrobial and cytotoxic activities were reported in this study. materials and methods: simultaneous distillation-extraction (sde) and gc-mass-fid analysis...