Antimicrobial treatments result in the host's enteric bacteria being exposed to the antimicrobials. Pharmacodynamic models can describe how this exposure affects the enteric bacteria and their antimicrobial resistance. The models utilize measurements of bacterial antimicrobial susceptibility traditionally obtained in vitro in aerobic conditions. However, in vivo enteric bacteria are exposed to ...

Early targeted antimicrobial therapy helps decrease costs and prevents the spread of antimicrobial resistance, including in Escherichia coli, the most frequent Gram-negative bacterium that causes sepsis. Therefore, rapid susceptibility testing represents the major prerequisite for knowledge-based successful antimicrobial treatment. To accelerate testing for antibiotic susceptibility, we have de...

abstract       background and objective: due to the continuous increase of multidrug-resistant acinetobacter baumannii strains around the world, decision making for an effective treatment of infections caused by this organism depends on the results of antimicrobial susceptibility tests. in this study, the validity of disk diffusion and e-test methods was assessed by their comparison with the re...

background bloodstream infection (bsi) is an important cause of mortality and morbidity and among the most common health-care associated infections. in this study we described the frequency of occurrence and antimicrobial susceptibility patterns of nosocomial and community-acquired bsi isolates from a teaching hospital in tehran, iran. patients and methods this cross-sectional study was conduct...

The aim of this study was to examine the antimicrobial susceptibility of 97 Haemophilus parasuis cultured from Australian pigs. As there is no existing standard antimicrobial susceptibility technique available for H. parasuis, methods utilising the supplemented media, BA/SN for disc diffusion and test medium broth (TMB) for a microdilution technique, were initially evaluated with the reference ...

background enterococci have emerged as more virulent and multidrug-resistant in community and hospital settings. the emergence of vancomycin resistant enterococci (vre) in hospitals has posed a serious threat to public health. the widespread use of antibiotics to treat vre infections has resulted in the development of resistant forms of these organisms. conclusions among the nanoparticles, zno ...