the first reaction between food components and biological tissues occurs in the oral cavity. saliva modulates the ecosystem in the oral cavity and plays a critical role in oral homeostasis. in addition, saliva is a first line of defense against free radical-mediated stress. salivary antioxidant defense mechanisms seem to be very important. in this study we discuss in detail free radicals (fr) a...

The manipulation of egg content is one of the few ways by which female birds can alter offspring quality before hatch. Lipid-soluble vitamins and carotenoids are potent antioxidants. Female birds deposit these antioxidants into eggs in variable amounts according to environmental and social conditions, and the quantities deposited into eggs can have effects on offspring health and immunological ...

background : periodontal disease is a common oral disease, which oxidative stress plays an important role in its pathogenesis. the onset and progress of this disease is influenced by balance between oral biofilm and host response. regarding with the role of oxidative stress in the pathogenesis of periodontal disease and reduction of total antioxidant capacity in patients with periodontal diseas...

If aging is due to or contributed by free radical reactions, as postulated by the free radical theory of aging, lifespan of organisms should be extended by administration of exogenous antioxidants. This paper reviews data on model organisms concerning the effects of exogenous antioxidants (antioxidant vitamins, lipoic acid, coenzyme Q, melatonin, resveratrol, curcumin, other polyphenols, and sy...

The role of antioxidants in the maintenance of health and prevention of disorders and diseases has received much attention. Above all, the action and effects of natural antioxidants contained in foods, fruits, spices, beverages and dietary supplements have been the subjects of extensive studies. The capacity of antioxidants has been assessed by various methods, but they often give inconsistent ...

2.1. Glutathione 2.1.A. Biological Functions 2.1.B. Biosynthesis 2.1.C. Degradation 2.1.D. Other Thiol-Based Redox Buffers 2.2. Ascorbate 2.2.A. Ascorbate Chemistry 2.2.B. Ascorbate Biosynthesis 2.2.C. Ascorbate Recycling 2.2.D. Ascorbate Transport 2.2.E. Importance of Ascorbate in Stress and Disease 2.3. Other Antioxidants 2.3.A. Lipid-Soluble Antioxidants 2.3.B. Water-Soluble Antioxidants 2.3...

Natural antioxidants are widely distributed in food and medicinal plants. These natural antioxidants, especially polyphenols and carotenoids, exhibit a wide range of biological effects, including anti-inflammatory, anti-aging, anti-atherosclerosis and anticancer. The effective extraction and proper assessment of antioxidants from food and medicinal plants are crucial to explore the potential an...

BACKGROUND Antioxidants have a preventive or therapeutic role in oxygen free radical-mediated cell and tissue damage. The study aimed to investigate the therapeutic effects of antioxidants and intranasal steroid fluticasone furoate (FF) on the clinical outcome of patients with perennial allergic rhinitis. METHODS Subjects with perennial allergic rhinitis (n = 61) were randomly divided into tw...

Antioxidants are molecules capable of inhibiting the oxidation of other molecules. Although oxidation reactions are essential for life, they can also be damaging. All living organisms maintain complex systems of multiple types of antioxidants to protect their cells from oxidative damage. Antioxidants can also act as pro-oxidants, under certain circumstances. The efficacy and benefit of an antio...

The incorporation of nitrogen atoms into the aromatic ring of phenolic compounds has enabled the development of some of the most potent radical-trapping antioxidants ever reported. These compounds, 3-pyridinols and 5-pyrimidinols, have stronger O-H bonds than equivalently substituted phenols, but possess similar reactivities toward autoxidation chain-carrying peroxyl radicals. These attributes ...