OBJECTIVE This study examines the antiretroviral (ARV) market characteristics for drugs procured and prescribed to Mexico's Social Protection System in Health beneficiaries between 2008 and 2013, and compares them with international data. MATERIALS AND METHODS Procurement information from the National Center for the Prevention and the Control of HIV/AIDS was analyzed to estimate volumes and p...

Prevention of mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) remains a challenge in most resource-limited settings, particularly in Africa. Single-dose and short-course antiretroviral (ARV) regimens are only partially effective and have failed to achieve wide coverage despite their apparent simplicity. More potent ARV combinations are restricted to pregnant w...

Pendahuluan: HIV (Human Immunodeficiency Virus) adalah sebuah virus yang menginfeksi pada sistem kekebalan tubuh manusia dan menyebabkan AIDS. dapat ditularkan melalui pertukaran cairan dari orang terinfeksi seorang ibu ke anaknya selama kehamilan persalinan. Pengobatan antiretroviral (ARV) menuntut ODHA untuk patuh menjalankan pengobatan secara teratur. Pemilihan obat serta pemberian belum cuk...

BACKGROUND Little is known about immunovirological treatment outcomes and adherence in HIV/AIDS patients on antiretroviral therapy (ART) treated using a simplified management approach in rural areas of developing countries, or about the main factors influencing those outcomes in clinical practice. METHODS Cross-sectional immunovirological, pharmacological, and adherence outcomes were evaluate...

The emergence of resistance to antiretroviral drugs is a major obstacle to the successful treatment of human immunodeficiency virus type 1 (HIV-1)-infected patients. In this work, we correlate clinical and virological trends such as viral load (VL) and CD4 counts to genotypic and phenotypic antiretroviral (ARV) resistance profiles of HIV-1 isolates from the B and non-B subtypes found in vertica...

The administration of isoniazid (INH) has been proposed, evaluated and implemented to prevent tuberculosis (TB) disease among patients who are infected with the human immunodeficiency virus (HIV). This strategy has been developed in communities where TB is highly endemic and at a time when antiretroviral (ARV) treatment was not, or was rarely available. Although INH prevention programmes were s...

HIV infection results in gastrointestinal (GI) tract damage, microbial translocation, and immune activation, which are not completely ameliorated with suppression of viremia by antiretroviral (ARV) therapy. Furthermore, increased morbidity and mortality of ARV-treated HIV-infected individuals is associated with these dysfunctions. Thus, to enhance GI tract physiology, we treated SIV-infected pi...

In accordance with the National AIDS Law, the Argentinian State is committed to supply antiretroviral medication (ARV) free of charge. Due to the complexity of the National ARV Program management process, and the fact that people with HIV/AIDS (PLHA) are the beneficiaries of the Program, it is considered relevant to ascertain their opinion. The aim of this work is to examine the supply of ARV b...

OBJECTIVES To estimate the prevalence of transmitted antiretroviral (ARV) drug resistance, and to assess whether resistance testing influences first-line ARV regimen selection. METHODS Data on patients' characteristics were collected through questionnaires. ARV drug resistance was tested by genotypic methods and defined by Quest-Stanford classification rule. Physicians reported the intended a...

Elderly HIV-infected patients may present particularities on both disease evolution and morbidity, as compared to younger patients. Moreover, elderly patients are more likely to take numerous medications due to their agerelated condition. VISAGE is a French multidisciplinary study group focusing on elderly HIV-infected patients in order to evaluate and improve their therapeutic care. Our study ...