Antiseptic preparations used repeatedly to disinfect the skin caused a reduction in yield of resident flora to a low equilibrium level beyond which further reduction did not occur. This equilibrium varied with the antiseptic preparation used. In a comparison of three preparations, the lowest equilibrium level was obtained with 95% ethyl alcohol. The further reduction in yield of skin bacteria o...

BACKGROUND Central venous catheter-related infections are a significant medical problem. Improved preventive measures are needed. OBJECTIVE To ascertain 1) effectiveness of a second-generation antiseptic-coated catheter in the prevention of microbial colonization and infection; 2) safety and tolerability of this device; 3) microbiology of infected catheters; and 4) propensity for the developm...

CONTEXT A recent randomized controlled trial and meta-analysis indicated that central venous catheters impregnated with an antiseptic combination of chlorhexidine and silver sulfadiazine are efficacious in reducing the incidence of catheter-related bloodstream infection (CR-BSI); however, the ultimate clinical and economic consequences of their use have not been formally evaluated. OBJECTIVE ...

background: super oxidized water (sow), as a novel antiseptic solution, is used with claims of effectiveness and cost effectiveness in healing chronic wounds such as diabetic foot, infectious post-operative ulcers and burn ulcers. we conducted a health technology assessment to evaluate the clinical evidence from clinical and randomized trials for this disinfection. this study aims to evaluate t...

The Food and Drug Administration (FDA, the Agency, or we) is issuing this final rule establishing that certain active ingredients used in nonprescription (also known as overthe-counter or OTC) antiseptic products intended for use by health care professionals in a hospital setting or other health care situations outside the hospital are not generally recognized as safe and effective (GRAS/GRAE)....

Dressing. ? In moat cases strict antiseptic precautions were taken. In the surgical wards of this hospital, Listerism was seldom practised before. Having observed during my studentdays the most excellent results of antiseptic surgery in the first Surgeon's wards of the Medical College Hospital and subsequently iu the wards of the Edinburgh Royal infirmary, the very scene of Listerian labour and...