The diarylurea is a scaffold of great importance in medicinal chemistry as it present numerous heterocyclic compounds with antithrombotic, antimalarial, antibacterial, and anti-inflammatory properties. Some diarylureas, serine-threonine kinase or tyrosine inhibitors, were recently reported literature. first to come into the market an anticancer agent was sorafenib, followed by some others. In t...

background: chemo-immunotherapy is one of the new achievements for treatment of cancer, by which the success of anti-cancer therapy can be increased. in vitro studies have been shown that arteether (are) induces apoptosis in tumor cells, but not in normal cells. objective: to investigate the cytotoxic and immunomodulatory properties of arteether in-vivo and in-vitro. methods: in this study, we ...

The antitumor activity of a new antibiotic, stubomycin, against various murine tumors was studied. Stubomycin showed antitumor activity against Sarcoma 180, IMC-carcinoma and Meth-A tumor. In particular, all of the mice inoculated i.p. with IMC-carcinoma were cured when they were given nine successive injections of stubomycin. Stubomycin also showed remarkable antitumor effects against Sarcoma ...

Background: The parasitic fungus Cordyceps sinensis (Ophiocordyceps sinensis) has been discovered in lepidopteran larvae, having known antitumor effects. Testing potentized cancer cells could help broaden Homoeopathy therapeutics.