نتایج جستجو برای: apoptosis

تعداد نتایج: 155680  

Journal: :iranian biomedical journal 0
فروزان آبسالان forouzan absalan منصوره موحدین mansoureh movahedin سید جواد مولی seyed javad mowla

introduction: cryptorchidism has been proved to cause apoptosis in germ cells in respond to changes in the stimulation levels of specific physiological events. the purpose of this study was to determine whether treatment of bilateral cryptorchidism was associated with alterations in testicular gene expression. methods: to induce bilateral cryptorchid model, immature mice were anesthetized and a...

Journal: :acta medica iranica 0
hamidreza ahmadi ashtiani cosmetic products research center, iran food and drug adminstration, ministry of health and medical education, tehran, iran. and department of basic sciences, school of veterinary medicine, university of tehran, iran. and pharmaceutical sciences branch, islamic azad university, tehran, iran. arash khaki department of pathology, faculty of veterinary, islamic azad university, tabriz, iran. shahram ejtemaei mehr department of pharmacology, tehran university of medical sciences, tehran, iran. soghra anjarani health reference laboratories, ministry of health and medical education, tehran, iran. manochehr dadgarnejad cosmetic products research center, iran food and drug adminstration, ministry of health and medical education, tehran, iran. mahmoud alebouyeh cosmetic products research center, iran food and drug adminstration, ministry of health and medical education, tehran, iran.

lead (pb), has, for decades, being known for its adverse effects on various body organs and systems. in the present study, the damage of pb on the liver tissue apoptosis was investigated, and lycopersicon esculentum as an antioxidants source was administered orally to prevent the adverse effects of pb. eighteen wistar rats, randomized into three groups (n=6), were used for this study. animals i...

Journal: :international journal of hematology-oncology and stem cell research 0
shahrbano rostami tarbiat modares university, tehran, iran saeid abroun tarbiat modares university, tehran, iran kamran alimoghaddam hematology-oncology and stem cell transplantation research center, tehran, iran mehrdad nourozinia tarbiat modares university, tehran, iran bahram chahardouli department of hematology, school of allied medical sciences, tehran university of medical sciences tehran, iran ardeshir ghavamzade hematology-oncology and stem cell transplantation research center, tehran, iran

introduction : arsenic trioxide (as2o3) causes antitumor effects by various mechanisms, including degradation of pml-rara in the acute promyelocytic cells, growth inhibition and induction of apoptosis. however, the precise mechanisms of these processes remain incompletely understood. the purpose of this study was to evaluate the effects of arsenic trioxide on cell growth, cell cycle regulation ...

Journal: :iranian journal of pathology 2011
majid asadi-shekaari hassan eftekhar vaghefi masoud ezzat abadi pour vahid sheibani ali shams ara

background and objective: as one of the widely used drugs, aspirin (acetyl-salicylic acid, asa) plays an important role in stroke treatment and prevention. in a previous study, we demonstrated asa injection at 30 min after ischemia onset is neuroprotective. to determine whether the neurons protected by asa had a normal ultrastructure, hippocampal ca1 pyramidal neurons were examined by transmiss...

Journal: :research in molecular medicine 0
alireza khalatbary molecular and cell biology research center, department of anatomy, faculty of medicine, mazandaran university of medical sciences, sari, iran. behrooz mohammadnegad department of anatomy, faculty of medicine, mazandaran university of medical sciences, sari, iran elmira ghaffari department of anatomy, faculty of medicine, mazandaran university of medical sciences, sari, iran alireza rafiei molecular and cell biology research center, department of immunology, faculty of medicine, mazandaran university of medical sciences, sari, iran

background: deltamethrin (dm) is a synthetic pyrethroid insecticide that can elicit neurotoxicity, and lead to apoptosis. there is accumulating evidence that oleuropein (oe) has anti-apoptotic effect. this study aimed at determining the dm toxicity and anti-apoptotic effect of oe pretreatment in cerebellar purkinje neurons. materials and methods: rats were randomly divided into four groups as f...

Journal: :gene, cell and tissue 0
afshar jafari department of exercise physiology, tabriz university, tabriz, ir iran hassan pourrazi department of exercise physiology, tabriz university, tabriz, ir iran; department of exercise physiology, tabriz university, tabriz, ir iran. tel: +98-4133393258, fax: +98-4133393257 saeid nikookheslat department of exercise physiology, tabriz university, tabriz, ir iran behzad baradaran department of immunology, tabriz university of medical sciences, tabriz, ir iran

conclusions in general, it seems that three-month exercise training was effective in reducing cardiac mitochondrial pro-apoptotic protein. however, considering the results of the bcl2 gene expression, more researches are needed to identify effects of exercise trainings on indices of myocardial apoptosis. objectives the aim of this study was to assess the effect of exercise training on bcl-2 and...

Journal: :Encyclopedia 2022

Apoptosis, programmed cell death, has a central role in developmental biology and maintaining the equilibrium of renewing tissues. A founding member Bcl-2 family regulatory proteins for apoptosis is Bcl-2, which encoded by BCL2 gene. Caspase-3 shares typical features with all caspases, including acting as crucial mediator apoptosis.

Journal: :cell journal 0

apoptosis, a form of programmed cell death that occurs under physiological as well as pathological conditions, is characterized by morphological and biochemical features. while the importance of caspases in apoptosis is established, several noncaspase proteases (ca2+-dependent proteases) such as calpain may play a role in the execution of apoptosis. the calpain family consists of two major isof...

Journal: :journal of skin and stem cell 0
zohreh jadali skin and stem cell research center, tehran university of medical sciences, tehran, iran; school of public health, tehran university of medical sciences, tehran, iran; skin and stem cell research center, tehran university of medical sciences, tehran, iran. tel: +98-2122215558, fax: +98-2122674977

Journal: :journal of fasting and health 0
mohammad derakhshan department of clinical bacteriology & virology, faculty of medicine, anti-microbial research center, mashhad university of medical sciences, mashhad, iran reza derakhshan school of medicine. mashhad university of medical sciences

fasting, that is usually described as abstinence from all food and drink for a period of time, has been experienced for ages. health, protest, religious expressions of devotion and purification are the most important reasons for fasting. many changes occur in the body during fasting including metabolic, mineral, hormonal, immunological and psychological. its use as one of the oldest therapies a...

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