Here we present a microfluidic platform to generate multiplex gradients of biomolecules within parallel microfluidic channels, in which a range of multiplex concentration gradients with different profile shapes are simultaneously produced. Nonlinear polynomial gradients were also generated using this device. The gradient generation principle is based on implementing parrallel channels with each...

We report the preparation of in-plane density gradients of amino-terminated molecules and gold particles through derivatization of laterally varying thickness gradients of poly(acrylic acid) (PAA) or poly(acrylamide) (PAAm) films. PAA and PAAm gradients were formed by Zn(II)-catalyzed electropolymerization of acrylic acid (AA) or acrylamide (AAm) in the presence of an in-plane electrochemical p...

Estimation of human orientation contributes to improving the accuracy of human behavior recognition. However, estimation of human orientation is a challenging task because of the variable appearance of the human body. The wide variety of poses, sizes and clothes combined with a complicated background degrades the estimation accuracy. Therefore, we propose a method for estimating human orientati...

This paper proposes a new state feedback control design for uniformly controllable linear time-varying systems. The new design is based on a nonlinear state transformation that converts the stabilization problem of the system state into a destabilization problem of the transformed state. Such a transformation results in a new control that has two advantages over previous controls. (1) In some o...

The asymptotic interdependence of the error probabilities exponents (reliabilities) in optimal hypotheses testing is studied for arbitrarily varying sources with state sequence known to the statistician. The case when states are not known to the decision maker was studied by Fu and Shen.

Using a transient mathematical heat transfer model including heat conduction, radiation, and radio frequency (RF) induction heating, we numerically investigate the time evolution of temperature gradients in axisymmetric growth apparatus during sublimation growth of silicon carbide (SiC) bulk single crystals by physical vapor transport (PVT) (modified Lely method). Temperature gradients on the g...

The ability to generate stable chemical gradients in microfluidics has important applications, since such gradients are useful in both chemical and biological studies. Growing evidence reveals that many cellular responses are specific to non-linear spatial gradients, hence a need to control complex concentration gradient profiles with and within microfluidics. In this paper, we present a struct...

Using transient and stationary mathematical heat transfer models including heat conduction, radiation, and radio frequency (RF) induction heating, we numerically investigate the time evolution of temperature gradients in axisymmetric growth apparatus during the sublimation growth of silicon carbide (SiC) bulk single crystals by physical vapor transport (PVT) (modified Lely method). Temperature ...

Many chemical and biological processes are dependent on molecular gradients. We describe a new microfluidic approach that can be used to produce spatiotemporal gradients across two-dimensional surfaces and three-dimensional gels under flow-free conditions. Free diffusion between dynamically replenished flow channels acting as a sink and source is utilized to give rise to stable steady-state gra...

We report a general diffusion based method to form micrometer-scale lateral chemical gradients in polymer brushes via selective alkylation. A quaternized brush gradient is derived from a concentration gradient of alkylating agent formed by diffusion in permeable media around a microchannel carrying the alkylating agent. Polymer brushes containing both charge and aromatic gradients are formed us...