Los ácidos nucleicos (ADN y ARN) tienen la importante función de almacenar, expresar transmitir información genética los seres vivos. El ADN actúa como "repositorio" información, en el núcleo las células, ARN mensajero (mRNA) transmite esa al sitio síntesis. Esta propiedad permite utilizar mRNA agente terapéutico o para generación inmunidad contra organismos patógenos. En particular es interesa...

BACKGROUND A case report of contralateral acute retinal necrosis (ARN) following herpes zoster ophthalmicus. CASE A 61-year-old male patient developed iridocyclitis and well-demarcated creamy-white retinal lesions at the nasal periphery in the right eye 1 month after herpes zoster ophthalmicus in the left eye. The patient had undergone surgery for primary lung cancer, and had subsequent intra...

Anticoagulant-related nephropathy (ARN) was initially described in patients on warfarin (as warfarin-related nephropathy) and recently in those using dabigatran. Herein, we report clinical history and kidney biopsy findings in a patient on apixaban (Eliquis). Initiation of treatment with apixaban resulted in aggravation of preexisting mild acute kidney injury (AKI). A few days after apixaban th...

AIM To determine an aetiological diagnosis in patients presenting with necrotising retinopathies that simulate acute retinal necrosis (ARN). METHODS Retrospective non-comparative case series. The charts of 16 patients presenting with a clinical impression of ARN at Pitie-Salpetriere Hospital, Paris, France, between 1994 and 1999, who required initial antiviral therapy were reviewed. All of th...

BACKGROUND To report a case of necrotizing herpetic retinopathy(NHR) in an immuno-compromised pediatric patient. CASE PRESENTATION An 11-year-old boy presented with a minimal ocular foreign-body sensation and peripheral visual-field defect, as well as mild upper respiratory symptoms. He had undergone the Fontan operation for a ventricular septal defect and single ventricle during infancy, and...

Commiphora caudata (Wight & Arn) is a potential medicinal plant used for its antispasmodic activity, cytotoxic activity and hypothermic activity. Owing to its medicinal importance, macroscopic and microscopic characters of leaves of Commiphora caudata were studied.

PURPOSE To describe the clinical features of complicated retinal detachment secondary to acute retinal necrosis (ARN) and to present the long-term results of vitreous surgery in these cases. METHODS A retrospective study was conducted on 16 immunocompetent patients (18 eyes). The average follow-up period was 60 months. RESULTS Proliferative vitreoretinopathy (PVR) grade C, with the predomin...

BACKGROUND/AIMS Varicella zoster virus (VZV) is a causative agent in acute retinal necrosis (ARN) syndrome. However, in spite of aggressive antiviral therapy, clinical characteristics among patients have varied. Different viral strains were examined to determine their respective role in producing clinical characteristics. The viral strains were also compared with those of previously reported on...

Hfq is an important RNA-binding protein that helps bacteria adapt to stress. Its primary function is to promote pairing between trans-acting small non-coding RNAs (sRNAs) and their target mRNAs. Identification of essential Hfq-binding motifs in up-stream regions of rpoS and fhlA led us to ask the question whether these elements are a common occurrence among other Hfq-dependent mRNAs as well. He...