BACKGROUND Artificial transcription factors (ATFs) are composed of DNA-binding and functional domains. These domains can be fused together to create proteins that can bind a chosen DNA sequence. To construct a valid ATF, it is necessary to design suitable DNA-binding and functional domains. The Cys2-His2 zinc finger motif is the ideal structural scaffold on which to construct a sequence-specifi...

-.J WPI was one of four colleges and universities awarded NASA grants for student design and development of an improved glove for space suits. This paper traces the design, development and testi ng of the WPI prototype glove. Test results showed that the glove did not significantly limit hand and finger motion when pressurized at 8 psi, except in the spherical grip mode. This project demonstrat...

On certain types of multi-touch touchpads, determining the number of finger stroke is a non-trivial problem. We investigate the application of several classification algorithms to this problem. Our experiments are based on a flat prototype of the spherical Touchglobe touchpad. We demonstrate that with a very short delay after the stroke, the number of touches can be determined by a Support Vect...

A prototype keyboard system was developed, using off-the-shelf hardware and software, as an inexpensive keyboard-based system to facilitate data entry for single-finger and typing-stick typists. Evaluation established that the system can increase entry rate by 50 percent or more. The underlying concepts may provide a basis for developing other configurations that accelerate and simplify compute...

There is a debate in the literature about whether the low- and high-frequency peaks of physiological finger tremor are caused by resonance or central drive. One way to address this issue is to examine the consequences of eliminating, as far as possible, the resonant properties or the voluntary drive. To study the effect of minimizing resonance, finger tremor was recorded under isometric conditi...

The problem of minimum-cost expansion of power transmission network is formulated as a genetic algorithm with the cost of new lines and security constraints and Kirchhoff’s Law at each bus bar included. A genetic algorithm (GA) is a search or optimization algorithm based on the mechanics of natural selection and genetics. An applied example is presented. The results from a set of tests carried ...