1 Primary treatment with amphotericin B or quickly switching from azoles to amphotericin B seems to be mandatory for good clinical outcome. There is no evidence of a clear correlation between the MICs of amphotericin B and outcome of treatment , but high MICs should be taken into consideration for antifungal alternatives. 7 The combination of amphotericin B with caspofungin could have been bene...

Aspergillosis of the lung is a very rare disease and is due chiefly to the Aspergillus fumigatus, but sometimes to A. niger, and, even more rarely, to the Aspergillus flavus. This disease is usually confused with pulmonary tuberculosis, and, in fact, sometimes coexists with it. Because there are on record very few such cases not co-existent with pulmonary tuberculosis, we have thought it desira...

This study was conducted to evaluate the effect of aqueous, ethanolic and ethyl acetate extracts from neem leaves on growth of some human pathogens (Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Candida albicans and Microsporum gypseum) in vitro. Different concentrations (5, 10, 15 and 20%) prepared from these extracts inhibited the growth of the test pathog...

background: the frequency of invasive opportunistic mycoses has increased significantly over the past decades especially in immunocompromised patients. invasive aspergillosis (ia) has become a major cause of morbidity and mortality among these patients. as bronchoalveolar lavage (bal) fluid samples are generally useful specimens in the diagnosis of invasive pulmonary aspergillosis (ipa), this s...

Objective: The main goal of study was finding the synergism effect of amphotricin B (AMB) and rifampin (RIF) on 3 species of Aspergillus. Methodology: Activities of amphotericin B in combination with rifampin were tested in buffered yeast-nitrogen base using checkerboard method. Plates were inoculated with 20μl spores suspensions of each organism and incubated at 30°C for 24h. For this method, ...

Aspergillus flavus is one of the most common contaminants that produces aflatoxins in foodstuffs. It is also a human allergen and a pathogen of animals and plants. Aspergillus flavus is included in the Aspergillus section Flavi that comprises 11 closely related species producing different profiles of secondary metabolites. A six-step strategy has been developed that allows identification of nin...

Aspergillus flavus is one of the most important plant as well as human pathogen. A. flavus, has gained worldwide attention for its industrial use and toxigenic potential. Besides their pathogenicity, A. flavus produces a wide range of secondary metabolites, used in food and pharmaceuticals industry. To determine the bioactivity of A. flavus, it was isolated from soil of Khyber Pukhtunkhwa, Paki...

Currently, researchers turn to natural processes such as using biological microorganisms in order to develop reliable and ecofriendly methods for the synthesis of metallic nanoparticles. In this study, we have investigated extracellular biosynthesis of silver nanoparticles using four Aspergillus species including A. fumigatus, A. clavatus, A. niger, and A. flavus. We have also analyzed nitrate ...

In the present study, novel real-time PCR assays targeting the fungal ITS2 region were developed for the detection and differentiation of medically important Aspergillus species (Aspergillus fumigatus, Aspergillus flavus, Aspergillus nidulans, Aspergillus niger, and Aspergillus terreus) and Candida species (Candida albicans, Candida dubliniensis, Candida glabrata, Candida krusei, Candida paraps...