conclusions the incidence of ipa in allogeneic hsct and patients with hematological malignancies was relatively high and a. flavus was the most common cause of pa. as molecular methods had higher sensitivity, it may be useful as screening methods in hsct and patients with hematological malignancies, or to determine when empirical antifungal therapy can be withheld. results seven (15.2%) out of ...

growth inhibition of aspergillus fumigatus,aspergillus flavus and fusarum solani exposed to the essential oils including thyme, agastache and satureja were studied. disc diffusion method was used to evaluate the fungal growth inhibitory effects of the essential oils. minimal inhibitory concentration (mic) and minimal fungicidal concentration (mfc) of the oils were determined and compared with e...

Azole resistance in Aspergillus fumigatus is an emerging public health concern. Recently, a novel fungicide-driven mutation in the cyp51A gene and its promoter, TR46/Y121F/T289A, leading to high-level resistance to voriconazole has been identified in The Netherlands, Belgium, Germany, Denmark, Tanzania, and India in both clinical and environmental samples. Here we report the first description o...

The fungitoxic properties of vapours of essential oil extracted from Cinnamon (Cinnamomum zeylanicum Breyn) bark have been investigated against five species of Aspergillus viz. A. flavus Link, A. fumigatus Fresenius, A. nidulans (Eidam) Wingate, A. niger van Tiegham and A. terreus Thom, causing biodeterioration of paper manuscripts in Gorakhpur. The fungitoxicity was determined in vitro as mini...

In this study, we examined the microbial population in different parts, gill, muscles and intestine region of Channa punctatus from two different fish culture farm. Based on their growth characteristics on specific culture media, the following human bacterial pathogen such as Achromobacter xylosoxidans (Gram +ve), Acinetobacter anitratus (Gram -ve), Bacillus subtilis (Gram +ve), Proteus vulgari...

The effect of corn and peanut cultivation on the proportion of Aspergillus flavus to A. parasiticus in soil was examined. Soil populations were monitored in three fields during three different years in southwestern Georgia. Each field was planted in both peanuts and corn, and soil was sampled within plots for each crop. A. flavus and A. parasiticus were present in similar proportions in plots f...

The in vitro antifungal activity of albendazole, a benzimidazole widely used as an antihelmintic drug in humans, was investigated and assessed for its activity against Aspergillus spp. Forty-eight isolates, representing the most frequent species found in human pathology [Aspergillus fumigatus (n = 27), Aspergillus flavus (n = 10), Aspergillus terreus (n = 7), Aspergillus nidulans (n = 3) and As...

In this study we attempted to modify the PCR-RFLP method using restriction enzyme MwoI for the identification of medically important Aspergillus species. Our subjects included nine standard Aspergillus species and 205 Aspergillus isolates of approved hospital acquired infections and hospital indoor sources. First of all, Aspergillus isolates were identified in the level of species by using morp...

Bronchopulmonary aspergillosis is usually caused by Aspergillus fumigatus. The six cases from the Sudan reported here were due to Aspergillus flavus. Three of the patients had primary invasive disease, one had Aspergillus mycetoma in a pre-existing lung cavity, and two had allergic aspergillosis. A special feature of the invasive disease was the clinical and radiographic simulation of malignanc...

Two anti-Aspergillus murine monoclonal antibodies (MAbs), designated 164G and 611F, have been produced; both specifically recognize cytoplasmic antigens of A. fumigatus, A. flavus, and A. niger by enzyme-linked immunosorbent assay. The MAbs can identify Aspergillus spp. both in frozen sections by immunofluorescence and in paraffin-embedded clinical specimens by immunofluorescence and immunopero...