objectives: diabetes mellitus is associated with biochemical, physiological and pathological alterations in the liver. the aim of this study was to investigate the effects of hydroalcoholic extract of prangos ferulacea (l.) lindle (p.f) on changes in rats´ liver structure and serum activities of alanin and aspartate aminotransferases after alloxan injection. materials and methods: in this study...

background: hepatic steatosis due to estrogen therapyincreases the activity of inflammatory markers, particularly theactivity of tnfα which in turn induces more lipogenesis.omega-3 fatty acids are among the negative regulators of hepaticlipogenesis. objectives: in this research, the preventive effectof omega-3 fatty acids on estrogen-induced steatosis in rats wasevaluated. methods:2 mg/kg. bw/s...

Various serum biomarkers have been developed for predicting head and neck squamous cell carcinoma (HNSCC) prognosis. However, none of them have been proven to be clinically significant. A recent study reported that the ratio of aspartate aminotransaminase (AST) to alanine aminotransaminase (ALT) had a prognostic effect on non-metastatic cancers. This study aimed to examine the effect of the AST...

CONTEXT Paracetamol (acetaminophen or APAP) is the most common pharmaceutical exposure in the US. Elevations in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels indicate hepatic toxicity. AST and ALT levels rise in similar proportions but later decline at different rates, with AST falling more rapidly than ALT. OBJECTIVE To determine whether the AST/ALT ratio can ind...

Background: The Centers for Medicaid and Medicare Services approved a number of panels as screening tests including those for liver functions. The utility of routinely testing for Aspartate aminotransferase (AST) and direct bilirubin was questioned and empirical data analyzed to suggest alternatives. Methods: Tests done over six months were examined for AST, ALT, total and direct bilirubin valu...

BACKGROUND Elevation of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is prominent in acute dengue illness. The World Health Organization (WHO) 2009 dengue guidelines defined AST or ALT ≥ 1000 units/liter (U/L) as a criterion for severe dengue. We aimed to assess the clinical relevance and discriminatory value of AST or ALT for dengue hemorrhagic fever (DHF) and severe den...