the role of chlamydia pneumoniae in asthma has drawn much attention in recent years. in this study we assessed the prevalence of c. pneumoniae infections in patients with chronic stable and acute exacerbation of asthma and compared it with normal population. twenty adult patients with chronic stable asthma and 21 patients with acute exacerbations of asthma and 41 matched control subjects were s...

Objective(s):Bone marrow-derived mesenchymal stem cells (BMSCs) have attracted significant interest to treat asthma and its complication. In this study, the effects of BMSCs on lung pathology and inflammation in an ovalbumin-induced asthma model in mouse were examined. Materials and Methods:BALB/c mice were divided into three groups: control group (animals were not sensitized), asthma group (an...

The response to glucocorticoids (GCs) therapy classifies severe refractory asthma (SRA) and mild asthma, so the glucocorticoid receptors (GCRs) gene expression may be involved in SRA pathogenesis. Thus, it is aimed to compare the expression levels of two GCR isoforms (GCRα and GCRβ) in SRA, mild asthmatics, and healthy controls. Total RNA was isolated from the peripheral blood mononuclear lymph...

Background Calprotectin is a cytosolic protein that belongs to the S-100 protein group with immunomodulatory and antiproliferative actions. The level of this protein increases in infection, inflammation, and malignancy. The aim of this study was to evaluate the level of...

Dr.Mirsadraei and colleagues performed an interesting study about the lung HRCT findings in chemical warfare patients who suffering from long-term pulmonary complications. They found that air trapping and mosaic attenuation were the most common lung HRCT findings. Also they divided patients in different clinical entities according to the lung HRCT findings (Bronchiolitis Oblitrans, pulmonary fi...

Asthma is one of the most prevalent chronic diseases worldwide, with a considerable increase, especially in children. It considered main cause childhood morbidity, school absenteeism, and limitations sports practice. The causes are multifactorial, their prevalence varies from region to region, thus verifying great disparity estimates asthma. In this sense, objective study investigate asthma, it...

ObjectivesTo assess whether adolescents with asthma experience a lower mental well-being and general health than their peers without asthma.Study designData from the Prevention Incidence of Asthma Mite Allergy study were used. At ages 11, 14, 17, 20 years, 2651, 2522, 2094, 2206 participants, respectively, completed questionnaires. Their parents questionnaires at 11 (n = 2660), 14 2338), 17 yea...

background :asthma is the most common respiratory disease with an increasing prevalence. on the other hand, obesity is also a challenging disease compromising health in human communities. this study sought to assess the correlation of asthma and body mass index (bmi) in occupational setting.   methods : this study was conducted in a cable manufacturing company in 2012. a total of 551 workers fr...

objective: this study aimed to investigate the prediction of asthma control on the basis of perceived stress, locus of control, and self-efficacy in adult patients with asthma.  methods: this was a descriptive-correlative and cross-sectional study.the solecty of this study is all asthmatic patients in tehran. our sample consisted of 100 participants who were selected by purposeful sampling meth...