BACKGROUND & AIMS In this study we report the effects of sunflower, virgin olive and fish oils on the lipid profile and antioxidant defence system in liver mitochondria from rabbits with experimental atherosclerosis. METHOD An atherogenic control group were fed for 50 days on a diet containing 3% lard and 1.3% cholesterol. Four groups were fed for an additional period of 30 days with a diet e...

An experimental, placebo-controlled study with rabbits was conducted to determine the role of Abana, an Ayurvedic preparation, on atherosclerosis. The results showed that Abana arrested the rise in TC, LDLc and VLDLc when administered along with an atherogenic diet for 60 days. In another phase of the study, when Abana was given from days 60-120 to rabbits who were made hyperlipidemic by feedin...

BACKGROUND Obesity, hypercholesterolemia, elevated triglycerides, and type 2 diabetes are major risk factors for metabolic syndrome. Hamsters, unlike rats or mice, respond well to diet-induced obesity, increase body mass and adiposity on group housing, and increase food intake due to social confrontation-induced stress. They have a cardiovascular and hepatic system similar to that of humans, an...

The present study was designed to evaluate the antihyperlipidemic effect of aqueous extract of Achyranthes aspera a in experimental rats fed with diet containing sesame oil. Hyperlipidemia and the effect of Achyranthes aspera in experimental rats were studied by assessing parameters such as cholesterol, phospholipids, freefattyacids and triglycerides in serum, liver, and heart and kidney tissue...

Rats fed on atherogenic diets containing 2% cholesterol and 0.5% cholic acid with or without 0.15% thiouracil were exposed to carbon disulphide (CS2) vapours (1 mg/l of air), five hours a day, six days a week for 6-10 months. Serum and aorta lipid contents were determined, and the extent of atherosclerotic changes was investigated. The following effects of chronic exposure to CS2 were found: (1...

Recent studies have correlated metabolic diseases, such as metabolic syndrome and non-alcoholic fatty liver disease, with the circadian clock. However, whether such metabolic changes per se affect the circadian clock remains controversial. To address this, we investigated the daily mRNA expression profiles of clock genes in the liver of a dietary mouse model of non-alcoholic steatohepatitis (NA...

little scientific information is available that has evaluated safflower (carthamus tinctorius) cake as a substitute to conventional ingredients in small ruminants diet. the objective of this work was to evaluate the effect of feeding safflower cake in total mixed rations (tmrs) on lamb and kid growth rates, carcass traits and meat fatty acid composition. two consecutive trials were conducted us...

We tested agents that might suppress the formation of fibrous plaques which are the significant lesions in human atherosclerosis. Six groups of rabbits were studied for 8 weeks: one group was fed a control diet and five groups received an atherogenic diet known to produce accumulations of connective tissue in arterial lesions. One group received only the atherogenic diet and the remaining four ...