BACKGROUND AND PURPOSE The detection of circulating particulate cerebral emboli using transcranial Doppler ultrasonography has been recently reported. It has been suggested that this method might allow discrimination between different embolic materials; this would be very useful for selecting specific pharmacological treatment in individual patients. This study was designed to identify those pa...

mm in length (1). This was performed in a large cohort of subjects and includes sites that do not contain significant obstructive disease. Although one segment was studied in each subject, each epicardial coronary artery is reflected in the total cohort (i.e., this is not a study of disease limited to the left main segment). Further, the volumetric approach defines segments by the fixed anatomi...

OBJECTIVE Elastin, an extracellular matrix protein, constitutes about 30% of the dry weight of the arteries. Elastolysis induced by inflammatory processes is active in chronic arterial diseases. However, elastogenesis in arterial diseases has received little attention. In this work we hypothesized that disordered elastogenesis is active in matrix remodeling in atheroma and abdominal aortic aneu...

BACKGROUND AND OBJECTIVE The immune and infectious alterations occurring in periodontitis have been shown to alter the development and severity of cardiovascular disease. One of these relationships is the translocation of oral bacteria to atheroma plaques, thereby promoting plaque development. Thus, the aim of this study was to assess, by 16s cloning and sequencing, the microbial diversity of t...

BACKGROUND AND AIMS The purpose of this study was to identify patients at the risk of cerebrovascular attack (CVA) by detecting calcified carotid artery atheroma (CCAA) in panoramic radiography and evaluating their risk factors. MATERIALS AND METHODS A total of 960 panoramic radiographs of patients above 40 years old were evaluated. Doppler Sonography (DS) was performed for patients who showe...

BACKGROUND The mechanism that confers adverse cardiovascular prognosis in patients with the metabolic syndrome (MetS) remains unclear. We sought to investigate the association of MetS and its component risk factors with progression of coronary atherosclerosis. METHODS We performed a systematic review of 3459 patients who participated in 7 clinical trials that monitored coronary atheroma progr...

The present study aimed to investigate potential gene markers for predicting the formation of carotid atheroma plaques using high‑throughput bioinformatics methods. The GSE43292 gene expression profile was downloaded from the Gene Expression Omnibus database. Following data processing, differentially expressed genes (DEGs) were screened using a paired t‑test in the Linear Models for Microarray ...

BACKGROUND Patients with atrial fibrillation (AF) are at risk for thromboembolism, and coexistent cardiovascular diseases could affect their prothrombotic profiles. The relationship between plasma hemostatic markers and aortic atherosclerosis was determined in patients with AF or in sinus rhythm (SR). METHODS AND RESULTS Sixty patients with nonrheumatic AF and 46 patients in SR who underwent ...

Four Black South Africans presented with cardiac failure which was diagnosed as being due to cardiomyopathy. Necropsy examination revealed that all 4 patients had had severe coronary atheroma and myocardial infarction during life.

THE EVOLUTION OF ATHEROMA. . . . . . . . 1000 Smooth Muscle Cell Migration and Proliferation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1000 Smooth Muscle Cell Death During Atherogenesis . . . . . . . . . . . . . . . . . . . . . . . . . . 1000 The Arterial Extracellular Matrix. . . . . . 1001 Angiogenesis in Plaques. . . . . . . . . . . . . . . 1001 Plaque Mineralization. . . . . ....