objective: atherosclerosis disease, inflammation and malnutrition have strong association with end stage renal disease (esrd). diabetes mellitus (dm) is the most commonly esrd causes. diabetic nephropathy (dn) could be associated with inflammation. type 2 diabetic patients with advanced nephropathy show the highest levels of inflammatory markers. this study was designed to determine the associa...

Atherosclerosis is a chronic immune inflammatory disease. Atherosclerosis and relevant disease are threatening human life and health. Oxygenized low density lipoprotein (oxLDL) is a molecular basis in the pathogenesis of atherosclerosis and able to induce inflammation, stimulate immune system and interfere with lipid metabolism in the occurrence and development of atherosclerosis. Antibody agai...

Hypertension and atherosclerosis are debilitating diseases that affect millions each year. Long-term consequences include but not limited to stroke, myocardial infarction, kidney failure. Platelet-activating factor (PAF) is a proinflammatory mediator synthesized from subclass of phosphatidylcholines increases platelet activation, leukocyte adhesion, infiltration macrophages, intracellular lipid...

Abstract Familial hypercholesterolemia (FH) is a hereditary dislipidemia. Patients present with extremely high level of low-density lipoprotein cholesterol (LDL-C), which is due to mutation in the gene of LDL receptor. Homozygous patients (HoFH) whose incidence is 1 in 1.000.000 are at high risk of premature aortic valve stenosis, and coronary artery atherosclerosis. In homozygous individual...

BACKGROUND Atherosclerosis of the thoracic aorta is associated with stroke. The association between hypertension, a major risk factor for stroke, and aortic atherosclerosis has not been determined in the general population. METHODS AND RESULTS Transesophageal echocardiography was performed in 581 subjects, a random sample of the Olmsted County (Minnesota) population aged >/=45 years participa...

metabolic syndrome (mets) as a collection of obesity-associated disorders is associated with inflammation, oxidative stress, pro-thrombotic state, elevated risk of developing cardiovascular disease and type 2 diabetes. adiponectin is one of the most abundant peptide hormones derived from adipose tissue. this protein plays a major role in glucose and lipid metabolism and prevents development of ...

abstract background and purpose: epicardial fat is the true visceral fat located around the heart, particularly around sub-epicardial coronary arteries that may locally interact and modulate the coronary arteries and myocardium through paracrine or vasocrine secretion of anti-inflammatory and proatherogenic cytokines. most previous studies have used echocardiography and reported controversial r...

objective: a magnesium deficiency is known to be involved in many abnormalities in the post-menopausal women. previous studies proposed that magnesium (mg) might prevent atherosclerosis. in this study the efficacy of serum magnesium level and its relation with carotid intima media thickness (cimt) in post-menopausal women was evaluated. methods: eighty iranian postmenopausal women were included...