Background and Objective: Ischemic heart disease (IHD) following atherosclerosis is the most common cause of cardiac deaths world wide. We aimed to investigate the pathologic features of atherosclerosis in non cardiac death cases to have an estimate of atherosclerosis prevalence in Mashad (North east of Iran). Patients and Methods : This descriptive (cross sectional) study was done, during ...

Background: Human leukocyte antigen (HLA) complex is a gene family involved in antigen presentation associated with protection or susceptibility to inflammatory, infectious and autoimmune diseases. Atherosclerosis is a chronic inflammatory disease in which HLA molecules play a role in the initiation and development of the disease through presentation of self or foreign antigens to T cells. Obje...

Background and Aims : Genome wide association studies revealed a strong between the CXCL12 gene locus cardiovascular diseases, highlighting its receptors CXCR4 atypical chemokine receptor-3 (ACKR3) as targets for CVD research. Although vascular is well studied in atherosclerosis, exact role of ACKR3 remains elusive. Therefore, aim this project to decipher atherosclerosis.

Atherosclerosis is an underlying cause of a broad array cardiovascular diseases characterized by plaques, arterial wall thickening initiated hyperlipidemia, pro-inflammatory signals, endothelial dysfunction and the influx inflammatory cells. By still incompletely mechanisms, these plaques can destabilize or erode, leading to thrombosis blood vessel occlusion becomes clinically manifest as angin...

Macrophages are known to play an important role in the initiation and progression of atherosclerosis; however, molecular signaling pathways macrophages that responsible for plaque rupture have not been fully identified. This study aims identify biomarkers therapy targets atherosclerotic conditions by systematic review. Research procedure reviews using PRISMA protocol. The search engine used thi...

Background: Atherosclerosis is an extremely predominant condition. The morbidity and mortality of cardiovascular cerebrovascular ailments caused by atherosclerosis have augmented significantly in recent years. discovery research new drugs are therefore obligatory will be cooperative the clinical treatment management atherosclerosis. Objective: Curcumol extracted from traditional Chinese medicin...