the aim of the present study was to clarify if old n-mri rat, a strain which is easily available in iran and cheap to maintain, is a suitable alternative to those previously reported. in this model, we compared three quantifiable parameters between old and young rats: biochemically, involving measurement of differences in the lipid profile. histologically, the differences of the thickness of th...

conclusions a significant proportion of coronary atherosclerotic plaques in cadavers with confirmed acute myocardial infarction were detected to be infected with cytomegaloviruses while no infections of c. pneumoniae and h. pylori were detected. patients and methods sixty cadavers in two equal groups were analyzed. acute myocardial infarction group included cadavers with acute myocardial infarc...

conclusion in cases with critical atherosclerotic disease of anterior tibial artery, pta-based biphasic or triphasic retrograde collateral flow prevents ischemia, whereas monophasic support or no retrograde flow remains incapable. results in the patient group, 31 lower limb arteries, of total of 17 cases, were included. after compression maneuver, dpa in 11 cases (six right, five left) showed r...

atherosclerosis is the most common cause of myocardial infarction and ischemic stroke. various risk factors have been identified for atherosclerosis. recently, bacterial and viral organisms, which are involved in chronic inflammatory processes, have been also implicated in atherosclerosis development. individuals with a prior history of periodontal diseases and/or tooth loss are considered to be...

background: atherosclerosis is a multifactorial disorder with chronic inflammatory conditions in which immune cells play a significant role in its pathogenic process. regulatory t cells (treg), as a part of immune system, are involved in controlling autoimmune and inflammatory diseases. quantitative and/or functional alteration of tregs has been shown to play an atheroprotective role and may al...

Trimethylamine N-oxide (TMAO) is a risk factor of various chronic diseases, which was produced by metabolism from precursors to trimethylamine (TMA) in gut and the oxidation TMA liver. The generation influenced diet, mainly due rich TMAO diet. However, it still unclear that effects different proportion source macronutrients dietary pattern on production process TMAO. Here, determined after sing...

Atherosclerosis is a chronic progressive condition in which the wall of artery develops abnormalities and causes thickening blood vessels. The development atherosclerosis complex process characterized by vascular inflammation growth atherosclerotic plaques that eventually lead to compromised flow. endothelial mesenchymal transition (EndMT) phenomenon whereby cells lose their properties acquire ...

Cardiovascular diseases (CVDs) still contribute as the main cause of mortality and premature worldwide. In Indonesia, CVDs to 35% death in non-communicable followed by diabetes at 6%. The ischemic heart disease acute stroke is Indonesia due atherosclerosis. Atherosclerosis a multifactorial cause, with chronic inflammation which causes myocardial infarction stroke. Research demonstrated that one...

Boesenbergia rotunda L., commonly known as fingerroot, is recognized one of Indonesia's medicinal plants with significant potential for treating various diseases, including atherosclerosis. This study aims to analyze the anti-atherosclerosis bioactive compounds found in fingerroot by assessing their inhibitory effects on four proteins associated atherosclerosis (CETP, ACAT1, OSC, and sPLA2). Bi...