BACKGROUND AND AIM The metabolic syndrome is a highly prevalent condition associated with cardiovascular disease. However, the contribution of LDL to cardiovascular risk is not estimated since it is not part of ATP III criteria. METHODS AND RESULTS This is an observational study evaluating the association between metabolic syndrome and carotid atherosclerosis, according to LDL cholesterol lev...

Peripheral vascular disease is circulation disorders that affect blood vessels outside of the heart and brain. Smoking tobacco main culprit for PVD. Management atherosclerosis plays an important role in adult medical care. The objective present study was to determine cardiovascular comorbidities associated with different stages peripheral current use pharmacological risk reducing therapy among ...

Chemokines and their receptors represent a potential target for immunotherapy in chronic inflammation. They comprise large family of cytokines with chemotactic activity, cognate are expressed on all cells the body. This network dictates leukocyte recruitment activation, angiogenesis, cell proliferation maturation. Dysregulation chemokine receptor expression as well function participates many pa...

Background and aim Systemic lupus erythematosus (SLE) have accelerated atherosclerosis and increased risk of cardiovascular disease. It is thought that the atherosclerosis process begins in the first decades of life and progresses silently. The aim of this study is to evaluate subclinical cardiovascular abnormalities including atherosclerosis and left ventricular hypertrophy (LVH) in children a...

Cardiovascular disease, predominantly coronary heart disease and stroke, leads to high morbidity and mortality not only in developed worlds but also in underdeveloped regions. The dominant pathologic foundation for cardiovascular disease is atherosclerosis and as to coronary heart disease, coronary atherosclerosis and resulting lumen stenosis, even total occlusions. In translational research, s...

Impaired Hemostasis To the Editor: There is mounting evidence that severely impaired hemostasis is associated with a decreased risk of ischemic cardiovascular disease. In a study with long follow-up, hemophilic patients had an 80% reduction in the risk of fatal ischemic heart disease.1 In clinical practice, occurrence of cardiovascular disease is uncommon in patients with type 3 severe von Will...

conclusions our results show a significant association of nos3 and mthfr gene polymorphisms with coronary atherosclerotic lesions. therefore, these variants might influence the risk of coronary artery disease, specifically in the iranian population. results we specifically detected the nos3 tt genotype in 12 patients (11.11%) and did not find the same genotype in any of the controls. the freque...

Cardiovascular diseases is one of the major public health and medical concerns globally. Atherosclerosis a condition where plaque build-up narrows blood vessels, ultimately preventing sufficient flow to heart. In current research, role played by human innate immune system in development atherosclerosis topic interest. Although specific relations require further studies, macrophages have been id...

BACKGROUND Atherosclerosis is complicated by cardiovascular events such as myocardial infarction, stroke, or peripheral arterial occlusive disease. Inflammation and pathological neovascularization are thought to precipitate plaque rupture or erosion, both causes of arterial thrombosis and cardiovascular events. We tested the hypothesis that arterial inflammation and angiogenic events are increa...