Atherosclerosis is the underlying pathology for cardiovascular disease. The preventive effects of tocotrienol-enriched mixed fraction (TEMF) on atherogenesis remains unclear. Objective: To investigate TEMF supplementation early and established atherosclerosis. Methods: Twenty New Zealand white rabbits were divided into (n=10) placebo groups. Treatments given by oral gavage 8 weeks followed 1% h...

background : the aim of this study was to detect fungi in atherosclerotic plaques and investigate their possible role in atherosclerosis. methods : coronary atherosclerotic plaques specimen were obtained from patients with atherosclerosis. direct exami-nation, culture, histopathology study, pcr and sequencing were performed to detect/identify the mycotic elements in the plaques. age, sex, smoki...

he 10 National Congress on Cardiovascular Update, organized by the Iranian Society of Atherosclerosis, was held in Tehran, Iran (June 11 – 14, 2008). A variety of issues related to advances in diagnostics and treatment in cardiovascular medicine were covered during the congress. Current problems of atherosclerosis, the role of platelets, and inflammatory biomarkers in its accelerated course wer...

Inflammatory reactions contribute to the pathogenesis of cardiovascular conditions such as atherosclerosis and ischemic damage in acute myocardial infarction (AMI). Among the mediators involved in inflammation are secretory phospholipase A2 group II (sPLA2-II) enzymes. Though some cells constitutively express sPLA2-II, the synthesis by cells such as hepatocytes is typical for an acute-phase rea...

Cardiovascular events, including myocardial infarction and stroke, are the primary causes of mortality in both type 1 and type 2 diabetes. Affected patients frequently have asymptomatic coronary artery disease. Studies have shown heterogeneity in cardiovascular risk among patients with diabetes. Imaging can help categorize risk of future cardiovascular events by identifying those patients with ...

BACKGROUND Atherosclerosis is increasingly considered to be a chronic inflammatory process. We examined whether genetic variants of the toll-like receptor 4 (TLR4), which are correlated with impaired innate immunity and with progression of carotid atherosclerosis, are also associated with coronary atherosclerosis and predict the risk of cardiovascular events. METHODS AND RESULTS Two polymorph...

more than 80% cardiovascular disease (cvd) is preventable despite the fact that it is currently the ultimate cause of disability in the world. assessment of the nationwide prevalence of dyslipidemia as a major cvd risk factor is essential to efficiently conduct prevention programs. we extracted data according to the cut‑off points of dyslipidemia used in each study. all published papers on this...

Curcumin, a natural polyphenolic compound present in Curcuma longa L. rhizomes, shows potent antioxidant, anti-inflammatory, anti-cancer, and anti-atherosclerotic properties. Atherosclerosis is comprehensive term for series of degenerative hyperplasic lesions such as thickening or sclerosis large- medium-sized arteries, causing decreased vascular-wall elasticity lumen diameter. Atherosclerotic ...