Topological indices are empirical features of graphs that characterize the topology graph and, for most part, independent. An important branch theory is chemical theory. In theory, atoms corresponds vertices and edges covalent bonds. A topological index a numeric number represents underline structure. this article, we examined properties prism octahedron network dimension <math xmlns="http://ww...

abstract: in this study an appropriate computational approach was presented for estimating the boiling temperatures of 41 different types of olefins and their derivatives. based on the guidelines of this approach, several structural indices related to the organic components were applied using graph theory. meanwhile, in addition to evaluating the relation between the boiling temperatures of ole...

Many studies have been conducted about the global topological nature of metabolic networks since the report by Barabasi's group [3]. Topological nature of networks depends on the definition of nodes and edges/arcs. In most of such studies, metabolites are assumed as nodes either in the studies conducted with or without the care of atomic tracing [1,3,4,5]. This is acceptable because the main fu...

the chromatic number of a graph g, denoted by χ(g), is the minimum number of colors such that g can be colored with these colors in such a way that no two adjacent vertices have the same color. a clique in a graph is a set of mutually adjacent vertices. the maximum size of a clique in a graph g is called the clique number of g. the turán graph tn(k) is a complete k-partite graph whose partition...

One of the most important targets in Alzheimer disease is Beta site amyloid precursor protein cleaving enzyme-1 (BACE-1). It is a membrane associated protein and is one of the main enzymes responsible for amyloid β (Aβ) production. Up to now, a considerable number of peptidic and non-peptidic inhibitors of BACE-1 have been developed. Recently, small molecule BACE-1 inhibitors have attracted the...

One of the most important targets in Alzheimer disease is Beta site amyloid precursor protein cleaving enzyme-1 (BACE-1). It is a membrane associated protein and is one of the main enzymes responsible for amyloid β (Aβ) production. Up to now, a considerable number of peptidic and non-peptidic inhibitors of BACE-1 have been developed. Recently, small molecule BACE-1 inhibitors have attracted the...

it is well known that the chemical behavior of a compound is dependent upon the structure of itsmolecules. quantitative structure – activity relationship (qsar) studies and quantitative structure –property relationship (qspr) studies are active areas of chemical research that focus on the nature ofthis dependency. topological indices are the numerical value associated with chemical constitution...