The effect of 2- pyridine aldoxime methyl chloride (2-PAMCl) and atropine with or without curcumin was investigated in dichlorvos (2,2-dichlorovinyl dimethyl phosphate; DDVP) induced toxicity in rats. Rats were exposed to DDVP (2 mg/kg sub-cutaneously) once daily for the period of 21 days. Post DDVP exposure, rats were further treated with 2-PAMCl (50 mg/kg intramuscular, once daily) + atropine...

The effects of atropine and glycopyrrolate on anatomical dead space, one and three second forced expiratory volume, maximal expiratory flow rate, and total forced expiratory volume were determined in ten healthy volunteers. Using Fowler's single breath nitrogen analyzing technique, atropine was found to increase dead space by 19.2 per cent at one hour, declining to 11.02 per cent at four hours....

Background: To date, guidelines on the impact and value of atropine combined with omeprazole in treatment acute gastritis have not been well established or defined. This study aimed to clarify efficacy safety therapy for management patients gastritis.

Abstract The present research study was aimed to investigate the efficiency of selected medicinal plants against Plasmodium vivax. Crude methanolic extracts from seeds leaves Datura stramonium , Parthenium hysterophorus Calotropis procera and Dodonaea viscosa were prepared. In addition, Atropine also isolated alkaloid components Eucalyptus obliqua evaluate their in vitro anti-plasmodial effects...

Myocardial protection from ischemic and reperfusion injury is an important task of modern experimental clinical medicine. This type damage a key link in the pathogenesis coronary heart disease and, above all, acute myocardial infarction – socio-economically significant that one main causes disability mortality adult population Republic Belarus. The aim study was to elucidate cardioprotective ef...

Some studies have shown that acetylcholine muscarinic receptors involved in the opiate reward. In the present study, the effect of intra-basolateral amygdale (BLA) acetylcholine muscarinic like receptor agonist (physostigmine) and antagonist (atropine) on the acquisition of morphine-induced place preference has been investigated in male Wistar rats. For this purpose, two 22 gauges guide cannula...

Atropine is the drug of choice for treatment of organophosphate nerve agent and insecticide intoxication and has been used for this indication for several decades. Adverse reactions to atropine may occur, and are of two types: toxic and allergic. Toxic reaction, the most common form, results from the anti-muscarinic effects of the drug. Since it is most probably related to interpersonal variati...

To determine the role of cholinergic reflexes on pancreatic secretory response to food, we studied the effect of atropine on amylase secretion in response to the octapeptide of cholecystokinin (CCK8) and to intraintestinal oleate. Four studies were done in six healthy volunteers. The duodenal content was aspirated by a double lumen tube while synthetic secretin (41 pmol/kg/h) was infused as a b...

Sir,—Jones and Drummond (1981) have shown that premedication with atropine does not influence the frequency of postoperative respiratory complications. However, they do not nuke a recommendation for routine use, or otherwise, of atropine in premedicatioa. Studies on the effects of atropine administration on ciliary activity have shown conflicting results. Experimental studies in dogs have not s...

Twenty-one patients with stable chronic obstructive pulmonary disease (mean FEV1 = 0.98 L) and high-normal serum theophylline levels (15-20 micrograms/ml) were evaluated in a randomized, double-blind fashion for additional bronchodilator response to aerosolized normal saline, atropine, or metaproterenol. Patients were classified as responders (R; n = 9) or nonresponders (NR; n = 12) to inhaled ...