Autoimmune blistering dermatoses (ABD) are a group of relatively rare autoantibody-driven diseases affecting primarily skin and/or multiple mucosa. They comprise of two main subdi‐ visions: ABD with autoimmunity to enzymes (dermatitis herpetiformis only) and ABD with autoimmunity to mostly structural proteins (anti-desmosomal autoimmunity circle, antidermal-epidermal junction autoimmunity circl...

Type 1 diabetes (T1D) and celiac disease (CeD) cluster in families and can occur in the same individual. Genetic loci have been associated with susceptibility to both diseases. Our aim was to explore the genetic differences between individuals developing both these diseases (double autoimmunity) versus those with only one. We hypothesized that double autoimmunity individuals carry more of the g...

BACKGROUND The link between type 1 diabetes and thyroid autoimmunity is well described. The same cannot be said for type 2 diabetes where results have been mixed so far. We investigated the prevalence and determinants of thyroid autoimmunity among Ghanaian type 2 diabetes patients. METHODS This was a case-control study involving 302 type 2 diabetes patients and 310 non - diabetic controls age...

In this review, we explore the role of dendritic cell subsets in the development of tissue-specific autoimmune diseases. From the increasing list of dendritic cell subclasses, it is becoming clear that we are only at the beginning of understanding the role of these antigen presenting cells in mediating autoimmunity. Emerging research areas for the study of dendritic cell involvement in the onse...