Abstract Background Non-healing surgical wounds is a risk in certain patients. Recently, allogenic plasma-rich-platelet (PRP) used such as regenerative treatment of different non-healing wounds. Purpose We explore the potential role using platelet-derived growth factors from single donor PRP, with freeze-thaw process, for scar ulcer. Methods have PRP preparation protocol that involved cycle cen...

BACKGROUND It is still not clear whether native or platelet count adjusted platelet rich plasma (PRP) should be used for platelet aggregation measurements. AIM To evaluate the necessity of using adjusted PRP in platelet function testing. METHODS Platelet aggregation with native PRP and adjusted PRP (platelet count: 250/nl, obtained by diluting native PRP with platelet poor plasma) was perfo...

Intraplatelet phospho-VASP analysis is a commonly used approach for monitoring of anti-platelet therapy; however, testing of intraplatelet phospho-VASP expression needs a high level of experience and proficiency. The ability to recognize how the pre-analytical variations can change the results would be helpful for the interpretation of data from intraplatelet P-VASP analysis. The aim of this st...

background: prp (platelet-rich plasma) is a biological product that has shown significant therapeutic results compared to synthetic drugs and some traditional methods. the advantages of this method include: prp, compared to other biological materials, is easily prepared in clinic and the safety is high as well. objectives: we aimed to investigate the evaluation of histomorphometric properties a...

Background: Among new therapies emerging in the medical field, use of platelet-rich plasma (PRP) human reproduction has not yet been explored. Platelet-rich a potential effect on tissue repair through proliferation and differentiation progenitor cells. The aim this study was to evaluate PRP testis structure function rabbit model. Material methods: A total 30 male rabbits were recruited study. T...

BACKGROUND Therapeutic success of platelet-rich plasma (PRP) may vary based on the composition and preparation method. The objective of this study was to evaluate the cellular components of platelet concentrates produced by a leucocyte-rich (LR-PRP) and a leucocyte-poor PRP systems (LP-PRP). METHODS Parameters evaluated included platelet recovery, platelet concentration, red blood cell (RBC) ...

  Objective: At present, growth factor-containing products such as enamel matrix derivatives, recombinant bone morphogenetic protein (rh-BMP), recombinant platelet derived growth factor and platelet rich plasma (PRP) have gained increasing attention. PRP is an autologous source of platelet growth factors used to enhance healing of soft and hard tissues. PRP has gained popularity due to its auto...

intraplatelet phospho-vasp analysis is a commonly used approach for monitoring of anti-platelet therapy; however, testing of intraplatelet phospho-vasp expression needs a high level of experience and proficiency. the ability to recognize how the pre-analytical variations can change the results would be helpful for the interpretation of data from intraplatelet p-vasp analysis. the aim of this st...

Background Recently, the clinical use of low power lasers has increased, and it is said that wound healing is accelerated by their irradiation. The aim of this study was evaluation of the effect of platelet-rich plasma on proliferation and differentiation of human dental pulp stem cells with or without Ga-Al-As laser. Methods: In this experimental study, human lower third molar dental pulp c...