Two studies were conducted to determine the efficacy of bacteriophage SPR02 and DAF6 at varying titers to treat colibacillosis in chickens. In Study 1, the treatments consisted of a control, i.m. injection of bacteriophage SPR02 or DAF6, Escherichia coli airsac challenge, and E. coli challenge followed by treatment at different titers with bacteriophage SPR02 or DAF6. The E. coli- challenged bi...

This study investigated whether the recently recognized emergence of canine streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis (NF) might be partly attributed to the use of fluoroquinolones to treat Streptococcus canis infections in dogs. Both mitomycin and the fluoroquinolone enrofloxacin caused bacteriophage-induced lysis of S. canis strain 34, an isolate from a case of canin...

The purpose of this investigation was to obtain further information on the time-temperature relationships in the heat inactivation of bacteriophage strains active against Streptococcus lactis and Streptococcus cremoris and to determine whether the heat resistance characteristics of various bacteriophage strains were related to other criteria used in bacteriophage classification. Harriman, in hi...

The production of cheese and other dairy products relies on the constant monitoring viruses, called bacteriophages, that attack organisms responsible for fermentation process. Bacteriophage species are characterized by a stable core genome, ‘genetic reservoir’ gene variants exchanged through recombination. Phylogenetic analysis phage populations notably difficult due not only to extreme levels ...

ADAMS, M. 1952 Classification of bacterial viruses: Characteristics of the T5 species and of the T2, C16 species. J. Bacteriol., 64, 387-396. BURNET, F. M. 1929 A method of study of bacteriophage multiplication in broth. Brit. J. Exp. Pathol., 10, 109-114. CHERRY, W. B., AND WATSON, D. W. 1949 The Streptococcu8 lactis host-virus system. II. Characteristics of virus growth and the effect of elec...

The effectiveness of bacteriophage P100, nisin and sodium lactate, individually and in combination, in inhibiting Listeria monocytogenes in ready-to-eat pork ham slices was assessed. The antimicrobials were applied to the surfaces of ready-to-eat pork ham slices, which were inoculated with a mixture of L. monocytogenes. Among the individual antimicrobial treatments, bacteriophage P100 was the m...

In order to control Pectobacterium carotovorum subsp. carotovorum, a novel virulent bacteriophage PM2 was isolated. Bacteriophage PM2 can infect 48% of P. carotovorum subsp. carotovorum and 78% of P. carotovorum subsp. brasilliensis but none of atrosepticum, betavasculorum, odoriferum and wasabiae isolates had been infected with PM2. PM2 phage belongs to the family Myoviridae, and contains a la...

Zernike phase contrast cryo-electron microscopy (ZPC-cryoEM) is an emerging technique that is capable of producing higher image contrast than conventional cryoEM. By combining this technique with advanced image processing methods, we achieved subnanometer resolution for two biological specimens: 2D bacteriorhodopsin crystal and epsilon15 bacteriophage. For an asymmetric reconstruction of epsilo...

The lysis of bacteria by bacteriophage was independently discovered by Frederick Twort 1 and Felix d’Herelle 2 but it was d’Herelle who proposed that bacteriophage might be applied to the control of bacterial diseases. Within the former Soviet Union (FSU), bacteriophage therapy was researched and applied extensively for the treatment of a wide range of bacterial infections. In the West, however...

Development of Human Complement System. Philip Fireman, Dolores A. Zuchowski and Paul M. Taylor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 Inactivation of Bacteriophage T4, of Poly-D-alanyl Bacteriophage and of Penicylloyt Bacteriophage by Immunospecifically Isolated IgM and I...