نتایج جستجو برای: balb/c

تعداد نتایج: 98  

Journal: :Behavioural brain research 2011
Maria Razzoli Lucia Carboni Michela Andreoli Alice Ballottari Roberto Arban

Social stress may precipitate psychopathological disorders in susceptible individuals. The present experiments were focused on the biology beyond the differential susceptibility to social stress. Social defeat, an ethologically relevant stressor known to elicit different coping strategies, was used in two mouse strains differing for baseline emotionality, such as C57BL6/J and BalbC. In separate...

Journal: :Physiology & Behavior 2015
Nathan P. Cramer Xiufen Xu Christine Christensen Alexis Bierman Clarke G. Tankersley Zygmunt Galdzicki

The interplay of environmental and genetic factors may lead to a spectrum of physiological and behavioral outcomes. How environmental stress factors interact with the diverse mouse genomes is still poorly understood and elucidating the underlying interactions requires specific stress models that can target integrated physiological systems. Here, we employ behavioral tests and whole-body plethys...

ژورنال: پژوهش در پزشکی 2013
بنده پور, مژگان, سلیمانی دارانی, معصومه, سید, نگار, شریف نیا, زرین, مصفا, نریمان, کاظمی, بهرام,

Abstract Background: Heat shock proteins, (Hsps) are used as adjuvants in vaccines these proteins induce the inflammatory cytokines and the maturation of monocyte MQ to dendritic cells. This study was done to determine the effect of Hsp90 on the immunogenicity of HbSAg in BalbC mice. Materials and methods: In this experimental study we injected Hsp90 β subunit together with HbsAg to 30 balbC mi...

2011
Wouter Oosterlinck Annelies Vanderper Willem Flameng Paul Herijgers

We investigated glucose tolerance and left ventricular contractile performance in 4 frequently used mouse strains (Swiss, C57BL/6J, DBA2, and BalbC) at 24 weeks. Glucose tolerance was tested by measuring blood glucose levels in time after intraperitoneal glucose injection (2 mg/g body weight). Left ventricular contractility was assessed by pressure-conductance analysis. Peak glucose levels and ...

Journal: :American journal of physiology. Heart and circulatory physiology 2002
Coert J Zuurbier Vanessa M Emons Can Ince

This study evaluates the effects of anesthesia and fluid support on hemodynamic parameters of the mechanically ventilated mouse of four different strains. All experiments were performed at a similar surgical level of anesthesia, as indicated by the probing of the pedal withdrawal reflex. Three anesthetic regimens [fentanyl-fluanisone-midazolam (FFM), ketamine-medetomidine-atropine (KMA), and is...

2016
Agustina Roldan‐Deamicis Eliana Alonso Belén Brie Diego Aguilera Braico Gabriela Andrea Balogh

The understanding of the molecular mechanisms of the immune tolerance induced by the tumoral microenvironment is fundamental to prevent cancer development or to treat cancer patients using immunotherapy. Actually, there are investigations about "addressed-drugs" against cancer cells without affecting normal cells. It could be ideal to find selective and specific compounds that only recognize an...

2012
Dallas C. Kinch James H. Peters Steven M. Simasko

Cholecystokinin (CCK) facilitates the process of satiation via activation of vagal afferent neurons innervating the upper gastrointestinal tract. Recent findings indicate CCK acts on these neurons via a ruthenium red (RuR) sensitive pathway that involves members of the vanilloid (V) subfamily of transient receptor potential (TRP) channels. To further test this mechanism, the mouse provides an i...

Journal: :Journal of neurophysiology 2004
Jiang Wu Neal S Peachey Alan D Marmorstein

In response to light, the retinal pigment epithelium (RPE) generates a series of slow potentials that can be recorded as the c-wave, fast oscillation (FO), and light peak (LP) of the electroretinogram (ERG). As these potentials can be related to specific cellular events, they provide information about RPE function and how that may be altered by disease or experimental manipulation. In the prese...

Journal: :Molecular medicine 2000
F B Riquet W F Lai J R Birkhead L F Suen G Karsenty M B Goldring

BACKGROUND Tissues undergoing a chronic inflammatory process, such as the synovium in rheumatoid arthritis, are characterized by the infiltration of lymphocytes of different subsets and activation of monocyte/macrophages. Interleukin-1 (IL-1), a monocyte/ macrophage product that stimulates synovial fibroblasts to produce matrix metalloproteinases (MMPs), prostaglandins, and other cytokines, als...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Jonathan Kipnis Tal Mizrahi Ehud Hauben Iftach Shaked Ethan Shevach Michal Schwartz

The ability of rats or mice to withstand the consequences of injury to myelinated axons in the CNS was previously shown to depend on the ability to manifest a T cell-mediated protective immune response, which is amenable to boosting by myelin-specific T cells. Here we show that this ability, assessed by retinal ganglion cell survival after optic nerve injury or locomotor activity after spinal c...

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