A better reduction of ambulatory venous hypertension in CVI individuals has been reported with high-pressure bandages in comparison to compression stockings which exert a lower pressure [7]. Moreover although higher pressure bandaging systems appear to be more efficient at ameliorating venous incompetence than lower pressure, the optimal amount and duration of compression is debateable [10]. In...

Uncontrolled bleeding from traumatic wounds is a major factor in deaths resulting from military conflict, accidents, disasters and crime. Self-assembling peptide nanofibers have shown superior hemostatic activity, and herein, we elucidate their mechanism by visualizing the formation of nanofiber-based clots that aggregate blood components with a similar morphology to fibrin-based clots. Further...

Biofilm formation in wounds is a serious problem which inhibits proper wound healing. One possible contributor to biofilm formation in a wound is the bacteria growing within the overlying bandage. To test this mechanism, we used bandages that contained a coating of organo-selenium that was covalently attached to the bandage. We tested the ability of this coating to kill bacteria on the bandage ...

A post-operative diabetic patient who had been treated for Serratia marcescens bacterial sepsis developed recurrent thrombosis of the left femoral artery following intra-arterial instrumentation. Pathological examination of arterial thrombus ultimately demonstrated invasive mucormycosis of the femoral artery and cultures of this material grew Rhizopus oryzae. The occurrence of cutaneous and sub...

Literature has shown that some patients with leg ulcers have a significantly poorer quality of life compared with those who do not have leg ulcers (Persoon et al, 2004; Briggs and Flemming, 2007). Table 1 shows that leg ulceration is a chronic condition, with many patients experiencing multiple problems, including (Stevens, 2006; Ellis, 2004; Persoon et al, 2004):  Pain  Discomfort  Social i...

Actico compression bandage system (Activa Healthcare) completes the prevention and treatment regime of venous leg ulcer management. Actico gives the patient comfort by being a simple two-layer compression bandage system that is also effective and which stays in place because of its cohesive nature. This product focus looks at the impact of venous leg ulcers, the use of compression and focuses o...

University of Vienna, Austria Conservative treatment of lymphoedema is based on decongestive lymphatic therapy (DLT) which consists of compression, manual lymphatic drainage (MLD), skin care and exercise. Some schools use the term complete decongestive physiotherapy (CDP) (Foeldi et al, 2003). The most important single component among these modalities is compression, for which several devices a...