The various parts of Melia dubia (Meliaceae) plant was observed to be used by the local tribes of Nilgiris for various infections. There was no report on antimicrobial activity of Melia dubia. Therefore, a preliminary phytochemical analysis and antimicrobial investigations were carried out on different extracts of Melia dubia bark. Ethanolic and aqueous extracts of the bark were found to posses...

The study was designed to evaluate the hepatoprotective activity of different solvent extracts (hexane, chloroform, ethyl acetate and methanol) of Enantia chlorantha stem bark in acute experimental liver injury induced by acetaminophen. The effects observed were compared with a known hepatoprotective agent, silymarin (100 mg/kg p.o.). Preliminary phytochemical tests and acute toxicity study wer...

The phytochemical and pharmacological studies of leaf, bark and fruit extracts of Samadera indica were carried out on aqueous and methanolic extracts, obtained by soxhlet technique. The qualitative tests showed the presence of carbohydrates, proteins, phenolics, alkaloids, saponins, flavonoids, tannins and resins, whereas quantitative estimations of carbohydrate, protein, phenolics and tannins ...

Nitric Oxide (NO) can autoregulate its own formation by feedback inhibition of the inducible Nitric Oxide Synthase (iNOS). Modulation of biosynthesis or activity of NO results in amelioration if pathogenesis of experimental arthritis. However, little is known about feedback mechanism on NO generation in response to carrageenan induced paw oedema and adjuvantinduced arthritis. In the present stu...

The phenolic composition of extracts from Uncaria tomentosa L. from different regions of Costa Rica was studied using advanced analytical techniques such as UPLC/TQ-ESI-MS and (13)C-NMR. Samples from leaves, stems, bark and wood (n = 22) were subjected to extraction to obtain phenolic and alkaloid extracts, separately. Comparatively, higher values of total phenolic content were observed for lea...

Symplocos racemosa Roxb bark belongs to the family: Symplocaceae. In Ayurveda it is known as Lodhra. The bark was collected and dried for four days under sun and powdered. It was extracted with different solvents ethanol, methanol and ethyl acetate by soxhlet hot extraction process. Preliminary phytochemical analysis was carried out for different extracts. It was found that saponin glycosides a...

Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and stem bark. In particular the lupane-, oleanane-, and ursane triterpenes display various pharmacological effects while being devoid of prominent toxicity. Therefore, these triterpenes are promising leading compounds for the development of new multi-targeting bioactive agents. Screening of 39 plant materi...

Isolation and identification of some potent anti-tumor compounds from medicinal plants, has motivated researchers to screen different parts of plant species for anti-tumor effects. It has been reported that several conifer posses cytotoxic activities on some human tumor cell lines. In this study, male and female branchlets or fruit of four different species of Iranian conifers (Juniperus Sabina...

Diospyros capricornuta is an endemic species widely distributed along the coast of Tanzania that used as food condiments and traditional medicine. The chemical compositions leaves, stem-bark, root-bark extracts; their bioactive potentials against Aspergillus flavus parasiticus were investigated. samples D. extracted using Soxhlet apparatus resultant extracts analyzed Gas Chromatography-Mass Spe...

The molluscicidal activity of Bauhinia variegata leaf and Mimusops elengi bark was studied against vector snail Lymnaea acuminata. The toxicity of both plants was time and concentration-dependent. Among organic extracts, ethanol extracts of both plants were more toxic. Toxicity of B. variegata leaf ethanolic extract (96h LC50- 14.4 mg/L) was more pronounced than M. elengi bark ethanolic extract...