Aggregation in traditional database systems is performed in batch mode: a query is submitted, the system processes a large volume of data over a long period of time, and an accurate answer is returned. Batch mode processing has long been unacceptable to users. In this paper we describe the need for online aggregation processing, in which aggregation operators provide ongoing feedback, and are c...

In this paper, we consider the batch mode reinforcement learning setting, where the central problem is to learn from a sample of trajectories a policy that satisfies or optimizes a performance criterion. We focus on the continuous state space case for which usual resolution schemes rely on function approximators either to represent the underlying control problem or to represent its value functi...

Dialkyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates have been prepared in a batch mode under conventional heating as well as under continuous flow conditions in the Miniflow 200SS, Sairem's microwave-assisted batch and continuous flow equipment. Real-time monitoring of the reactions by Raman spectroscopy enabled to compare both heating modes and to determine (optimized) reaction times.

* Corresponding author. Tel.: +351 22 5580001; fax E-mail address: [email protected] (P. Teixeira) The aim of this work was to characterize Enterococcus spp. isolated from Alheira, Chouriça de Vinhais and Salpicão de Vinhais, fermented meat products produced in the North of Portugal, concerning their potential pathogenicity. One hundred and eighty two isolates (76 identified as Enterococcus...

We study a novel problem of batch mode active learning for networked data. In this problem, data instances are connected with links and their labels are correlated with each other, and the goal of batch mode active learning is to exploit the link-based dependencies and node-specific content information to actively select a batch of instances to query the user for learning an accurate model to l...

Aminoacyl-tRNA synthetases catalyze the formation of an aminoacyl-AMP from an amino acid and ATP, prior to the aminoacyl transfer to tRNA. A subset of aminoacyl-tRNA synthetases, including glutamyl-tRNA synthetase (GluRS), have a regulation mechanism to avoid aminoacyl-AMP formation in the absence of tRNA. In this study, we determined the crystal structure of the 'non-productive' complex of The...

The main target in the production of monoclonal antibodies (MAbs) is reduction of operating costs. One of the pertinent challenges is improving the yield of MAbs through the reduction of secondary metabolic products. Therefore searching for an optimal nutrients supplying strategy becomes mandatory. This study is about the influence of by-products together with the dead cell concentration upon t...

Simultaneous Localization and Mapping (SLAM) from a monocular camera has been a well researched area. However, estimating camera pose and 3d geometry reliably for egocentric videos still remain a challenge [25, 40, 42]. Some of the common causes of failures are dominant 3D rotations and low parallax between successive frames, resulting in unreliable pose and 3d estimates. For forward moving cam...

The relationship between lipid content and tolerance to freezing at -50 degrees C was studied in Saccharomyces cerevisiae grown under batch or fed-batch mode and various aeration and temperature conditions. A higher free-sterol-to-phospholipid ratio as well as higher free sterol and phospholipid contents correlated with the superior cryoresistance in dough or in water of the fed-batch-grown com...

Cell-free protein synthesis is becoming a useful technique for synthetic biology. As more applications are developed, the demand for novel and more powerful in vitro expression systems is increasing. In this work, an all Escherichia coli cell-free system, that uses the endogenous transcription and translation molecular machineries, is optimized to synthesize up to 2.3 mg/ml of a reporter protei...