protein losing enteropathy (ple) as an initial finding of lymphoma, is extremely rare in childhood. we describe clinical and pathological features of an unusual case of gastrointestinal lymphoma presented with ple as a sole manifestation. differential diagnosis in children presenting with ple is critical because early diagnosis and treatment are important for survival in patients with lymphoma.

non hodgkin lymphoma (nhl) constitutes 5% of all head & neck cancer. the incidence of it has been increased over the last four decades. one of main characteristic of nhl is extranodal presentation that has different pattern in various part of world. a retrospective was designed in a tertiary referral center. it has been done between january 1996 and march 2006. all clinical and pathological cha...

cells produce and release granzyme B similarly to CD8 T cells, an activity not found in CD4 CD25 T cells. The authors further demonstrate that Bcell apoptosis mediated by CD4 CD25 T cells can be antigen dependent. CD4 CD25 T cells from mice bearing a transgenic TCR that recognizes an ovalbumin peptide were used for these experiments. Proliferating B cells were divided into 2 separate groups, on...

background epstein barr virus (ebv) is one of the most common viral infections in human population. ebv has a significant role in pathogenesis of hodgkin's lymphoma, burkitt's lymphoma and nasopharyngeal carcinoma. the role of ebv in non-hodgkin’s lymphoma, diffuse large b cell (nhl - dlbl) in the head and neck is controversial. objectives the purpose of this study is to find out the ...

Introduction: Burkitt lymphoma is an aggressive subtype of Hodgkin lymphoma with a doubling time of 25 hours. It is characterized by a MYC gene coding alteration which results from a translocation of chromosome 8 on the MYC gene locus and immunoglobulin heavy-chain locus (IGH) on chromosome 14. Even though HIV infection is associated to an increased risk of Burkitt lymphoma, th...

despite multiple published studies reporting result of salvage regimens for relapsed and refractory hodgkin's lymphoma, there are no comparisons of different combinations.a total of 44 patients identified with refractory or relapsed hodgkin's lymphoma were considered eligible for this study. the patients were randomly divided into two groups of 22, one of which were treated with gdp regimen (ge...

introduction: lymphomas as a group rank seventh as the most leading cause of death in cancers. stomach is the most common extra nodal site of primary lymphomas. on the other hand, new information demonstrates that malt lymphoma responds to helicobacter antibiotic therapy. we therefore decided to determine the frequency of distribution of helicobacter pylori infection in primary gastric lymphoma...

Background: Although cervical malignancy rate had grown up in recent years, primary cervical lymphoma is so rare. It must be high index of suspicious for primary cervical lymphoma diagnosis in patient with malignancy-like signs and symptoms for early detection. Primary cervical lymphoma has no standard treatment or follow-up protocol; so the management still is in doubt and based on previous ca...

our goal in this paper is to describe and compare basic immunopathologic pattern of common demyelinating disorder, that is very important to choose the best treatment. The most common disorders are multiple sclerosis, neuromyelitis optica,Anti MOG associated disease,ADEM and autoimmune encephalitis. ADEM consists of ‘‘sleeves’’ of demyelination centered on small, engorge...