background: in order to deworm the ruminants especially of sheep in iran, consumption of benzimi­dazoles has more than 2 decades history and today farmers are using imidazothiazoles, macrocyclic lactones and mostly benzimidazole compounds (bzs) to treat infected farm animals. it has been demonstrated that the most common molecular mechanism leading to bzsresistance in haemonchus contortus is a ...

In the title compound, [Zn(C(8)H(5)N(2)O(2))(2)(H(2)O)], the Zn(II) ion is coordinated in each case by a carboxyl-ate O atom and an imidazole N atom from two different benzimidazole-2-carboxyl-ate (BIC) ligands and one water O atom in a trigonal-bipyramidal geometry. In the complex mol-ecule, the two benzimidazole planes are twisted, making a dihedral angle of 55.93 (11)°. The three-dimensional...

In the mol-ecule of the title compound, C(22)H(18)Cl(2)N(2)O, the planar benzimidazole ring system is oriented with respect to the phenyl and dichloro-benzene rings at dihedral angles of 12.73 (3) and 36.57 (4)°, respectively. The dihedral angle between the dichloro-benzene and phenyl rings is 29.95 (6)°. There are C-H⋯π contacts between the benzimidazole and dichloro-benzene rings, between the...

In the title compound, C(29)H(28)N(4)O(3), the pyrrolidine ring adopts a twist conformation whereas the oxindole and benzimidazole residues are approximately planar with maximum deviations of 0.159 (1) and 0.011 (1) Å, respectively. The oxindole residue is almost perpendicular to the benzimidazole residue, making a dihedral angle of 89.2 (1)°. The methyl-substituted benzene ring is oriented at ...

The phototransformation of benzimidazole (BZ) and of the benzimidazole pesticide thiabendazole (TBZ) was investigated in aqueous solution in the absence and presence of the supramolecular host cucurbit[8]uril (CB8). ESI-MS and NMR reveal that both compounds form stable 1 : 2 host-guest complexes with CB8 (BZ2@CB8, TBZ2@CB8). The phototransformation of free BZ leads to dehydrodimerization, while...

In the cation of the title compound, C(14)H(13)N(2)S(+)·Br(-), the essentially planar benzimidazole system (r.m.s. deviation = 0.0082 Å) is substituted with a 4-methyl-sulfanylphenyl ring. The dihedral angle between the benzimidazole system and the 4-methyl-sulfanylphenyl ring is 2.133 (2)°. The crystal structure is characterized by strong and highly directional inter-molecular N-H⋯Br hydrogen ...

In the title compound, C(10)H(8)N(3)S(+)·NO(3) (-)·H(2)O, one of the N atoms of the benzimidazole unit is protonated, unlike than that in the thia-zole group. This protonation leads to equalization of the bond angles at the two N atoms of the benzimidazole group. The benzimidazole and thia-zole systems are almost coplanar, forming a dihedral angle of 0.5 (2)°. In the crystal, the nitrate anion ...

in this report, β-tubulin gene polymorphism was investigated in haemonchus contortus  populations isolated from sheep flocks in different regions of khouzestan province, southwestern iran. the samples were chosen on the basis of regional variation in benzimidazole treatment background of sheep flocks. our objective was to study the relationship between treatment background andβ -tubulin gene po...

A series of N’, N’’-[1-(1H-benzimidazole-2-yl)-2-(4-substituted phenyl ethane-1, 2-diyl)] substituted aromatic amines (AK1AK6) and hydrazides (AKH6 – AKH11) were synthesized by treating 2-methyl benzimidazole with different substituted aromatic aldehydes in the presence of ethanol to produce 2-[2-(4 chlorophenyl)-vinyl]-1H-benzimidazole. It was brominated to 2-[1, 2 dibromo 2-(4-substituted phe...

The title mol-ecule, C20H20N2S2, is T-shaped and consists of a nearly flat 5,6-dimethyl-2-(5-methyl-thio-phen-2-yl)benzimidazole system approximately perpendicular to the 5-methyl-thio-phen-2-ylmethyl substituent. The 5,6-dimethyl-2-(5-meth-yl-thio-phen-2-yl)benzimidazole system is rotationally disordered about the two imidazole N atoms as approximated by a twofold rotation axis with a refined ...