Three new biphenyls, berbekorin A (1), 2'-hydroxy-3,4,5-trimethoxybiphenyl (2), and 4,5-dihydroxy-3-methoxybiphenyl (3), together with 11 known biphenyls (4-14), were isolated from the n-hexane-soluble fraction of the MeOH extract of the trunk of Berberis koreana. The structures of 1-3 were determined by spectroscopic methods, including 1D and 2D NMR analysis. Compound 1 exhibited cytotoxic act...

Daruharidra (Berberis aristata DC) has been used in ayurveda and traditional Chinese medicine for more than 3000 years. It is a red-listed endemic medicinal plant species of conservation concern and has become very important in recent years due to its rarity and huge demand in the medicinal plant sector. However, many other species such as Berberis asiatica Roxb., Berberis lycium Royle., Cosini...

A reference extractive, containing multiple active known compounds, has been considered to be an alternative to individual reference standards. However, in the Chinese Pharmacopoeia (ChP) the great majority of reference extractives have been primarily used for qualitative identification by thin-layer chromatography (TLC) and few studies on the applicability of reference extractives for quantita...

The present study was designed to investigate antimicrobial and anti-inflammatory activities of four plant species from Indian origin. The antimicrobial activity of petroleum ether, chloroform, ethyl-acetate and methanol extracts of barks of Acacia nilotica, Berberis chitria, Terminalia paniculata and Madhuca longifolia were tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcu...

Berberis aristata commonly known as “Daru haldhi and Chitra” is spinous herb native to northern Himalaya region. The plant is widely distributed from Himalayas to Srilanka, Bhutan, and hilly areas of Nepal. Berberis aristata is used in ayurvedic medicines from very long time. The plant is used traditionally in inflammation, wound healing, skin disease, menohrrhagia, diarrhea, jaundice and affec...

BACKGROUND Berberine is an isoquinoline alkaloid widely used to improve the glucidic and lipidic profiles of patients with hypercholesterolemia, metabolic syndrome, and type 2 diabetes. The limitation of berberine seems to be its poor oral bioavailability, which is affected by the presence, in enterocytes, of P-glycoprotein - an active adenosine triphosphate (ATP)-consuming efflux protein that ...

The life history of Puccinia striiformis remains a mystery because the alternate host has never been identified. Inoculation of grasses using aeciospores from naturally infected Berberis chinensis and B. koreana resulted in infection on Poa pratensis, producing uredinia typical of stripe rust caused by P. striiformis. Analyses using real-time polymerase chain reaction and DNA sequence confirmed...

Research on biochemical properties of Berberis vulgaris which has diverse usage areas has increased the popularity of this plant. In this study, antioxidant properties, organic acid contents and phenolic compound contents of Berberis vulgaris fruits naturally grown in Gevaş Region (Van Province/Turkey) were determined. With respect to organic acids, malic acid content was found as 1.862 g/kg, c...