Clinical application of antimicrobial peptides (AMPs), as with conventional antibiotics, may be compromised by the development of bacterial resistance. This study investigated AMP resistance in methicillin resistant Staphylococcus aureus, including aspects related to the resilience of the resistant bacteria toward the peptides, the stability of resistance when selection pressures are removed, a...

conclusions the results showed that enterococci are common contaminants in food. indeed, this study indicates a high prevalence of multidrug-resistant enterococci in food of animal origin in iran. isolating some persisting enterococcal isolates revealed that continuous surveillance of antimicrobial resistance in enterococci from food is essential. materials and methods thirty samples of meat, c...

The present work was designed to assess the antibacterial properties of the methanol extracts of some Cameroonian medicinal plants and the effect of their associations with currently used antibiotics on multidrug resistant (MDR) Gram-negative bacteria overexpressing active efflux pumps. The antibacterial activities of twelve methanol extracts of medicinal plants were evaluated using broth micro...

The antimicrobial and cytotoxic effects of sodium hypochlorite (NaOCl) and sodium dichloroisocyanurate (NaDCC) were evaluated and compared in vitro. The minimal inhibitory concentration and minimal bactericidal concentration of NaOCl and NaDCC were tested for Streptococcus sobrinus, Streptococcus salivarius, Enterococcus faecalis, and Streptococcus mutans. The cytotoxic effect was assessed by u...

Salmonella enterica serovar Typhimurium is one of the most common serovars isolated from humans and livestock, and over 35% of these isolates are resistant to three or more antibiotics. Multidrug-resistant (MDR) Salmonella is a public health concern as it is associated with increased morbidity in patients compared to antibiotic sensitive strains, though it is unknown how the antibiotic resistan...

Cefotaxime, a new semisynthetic cephalosporin derivative, showed a broad spectrum of antibacterial activity against clinically isolated strains of gram-positive and gram-negative bacteria. This cephalosporin was slightly less active than cefazolin against Staphylococcus aureus but 4 to 300 times as active as carbenicillin against gram-negative organisms, including Pseudomonas aeruginosa, Pseudo...

The antimycobacterial activities of disulfiram (DSF) and diethyldithiocarbamate (DDC) against multidrug- and extensively drug-resistant tuberculosis (MDR/XDR-TB) clinical isolates were evaluated in vitro. Both DSF and DDC exhibited potent antitubercular activities against 42 clinical isolates of M. tuberculosis, including MDR/XDR-TB strains. Moreover, DSF showed remarkable bactericidal activity...

This study investigated the synergy testing of penicillin, cephalosporin, amphenicols, and aminoglycoside in camel milk (n=768 samples), subsequently used for isolation MDR S. aureus targeting mecA gene. Antibiotic susceptibility showed >90% isolates were sensitive to ciprofloxacin trimethoprim resistant against oxacillin, ampicillin, cefoxitin. Further, 50-85% gentamicin, oxytetracycline, chlo...

Objective: In the present study described here, we set out to look into quorum sensing inhibitory activity of methanolic seed extract Berberis crataegina DC. through -controlled inhibition violacein pigment production in Chromobacterium violaceum ATCC 12472. addition, antibacterial on various Gram-negative and Gram-positive standard strains was evaluated. Also phenolic contents were detected by...