γ-aminobutyric acid (GABA) or glucagon-like peptide-1 based drugs, such as sitagliptin (a dipeptidyl peptidase-4 inhibitor), were shown to induce beta cell regenerative effects in various diabetic mouse models. We propose that their combined administration can bring forth an additive therapeutic effect. We tested this hypothesis in a multiple low-dose streptozotocin (STZ)-induced beta cell inju...

We prepared a candidate primary reference material for the forthcoming international standardisation of beta-N-terminal glycated hemoglobin A measurements. It consists of well-defined mixtures of purified beta-N-terminal glycated hemoglobin A and non-glycated hemoglobin A. First, beta-N-terminal glycated hemoglobin A and non-glycated hemoglobin A were isolated, purified to homogeneity, and char...

Additive manufacturing technology provides a gateway to completely new horizons for producing wide range of components, such as manufacturing, medicine, aerospace, automotive, and space explorations, especially in non-conventional processes. The present study analyzes the influence additive manufactured tool electrochemical micromachining (ECMM) on machining beta titanium alloy. different param...

Nitroxyl anion (HNONO(-)), the one-electron reduced form of nitric oxide (NO), induces positive cardiac inotropy and selective venodilation in the normal in vivo circulation. Here we tested whether HNO/NO(-) augments systolic and diastolic function of failing hearts, and whether contrary to NO/nitrates such modulation enhances rather than blunts beta-adrenergic stimulation and is accompanied by...

In 1940, Ulam [1] proposed the famous Ulam stability problem of linear mappings. In 1941, Hyers [2] considered the case of approximately additive mappings f : E→ E′, where E and E′ are Banach spaces and f satisfies Hyers inequality ‖ f (x+ y)− f (x)− f (y)‖ ≤ ε for all x, y ∈ E. It was shown that the limit L(x) = limn→∞ 2−n f (2nx) exists for all x ∈ E and that L : E→ E′ is the unique additive ...

During signal transmission, the combined effect of the transmitter filter, the transmission medium, and additive white Gaussian noise (AWGN) are included in the channel which distort and add noise to the signal. This causes the well defined signal constellation to spread causing errors in bit detection. A compact pi neural network with minimum number of nodes is proposed. The replacement of sum...

Bresar in 1993 proved that each biderivation on a noncommutative prime ring is a multiple of a commutatot. A result of it is a characterization of commuting additive mappings, because each commuting additive map give rise to a biderivation. Then in 1995, he investigated biderivations, generalized biderivations and sigma-biderivations on a prime ring and generalized the results of derivations fo...