1. THE English Life Tables Nos. 8 to 13 are based on the population figures by age obtained at the successive censuses of England and Wales from 1911 to 1971 and the deaths recorded in the three calendar years centred on the census year. Over this 60-year period there have been changes in the information sought regarding age at census and death registration and improvements in the exposed-to-ri...

Next generation sequencing technology provides a powerful tool for measuring gene expression (mRNA) levels in the form of RNA-sequence data. Method development for identifying differentially expressed (DE) genes from RNA-seq data, which frequently includes many low-count integers and can exhibit severe overdispersion relative to Poisson or binomial distributions, is a popular area of ongoing re...

In this article, we present a general procedure to analyze exchangeable binary data that may also be viewed as realizations of binomial mixtures. Our approach unifies existing models and is practical and computationally easy. Resulting from completely monotonic functions, we introduce a rich family of parametric parsimonious binomial mixtures, including the incomplete Beta-, Gamma-, Normal-, an...

The indifference valuation problem in incomplete binomial models is analyzed. The model is general in that the stochastic factor which generates the marlet incompleteness may affect the transition propabilities and/or the values of the traded asset as well as the claim’s payoff. Two pricing algorithms are constructed which use, respectively, the minimal martingale and minimal entropy measures. ...

OBJECTIVES If in a clinical trial prognostic factors are known in advance, it is often recommended that randomization of patients should be stratified. The best-known method is permuted-block randomization within strata. But it suffers from the disadvantage that imbalance still occurs in the trial as a whole if there are a large number of strata, or/and the block sizes are too large for the num...

The binary power law (BPL) has been successfully used to characterize heterogeneity (overdispersion or small-scale aggregation) of disease incidence for many plant pathosystems. With the BPL, the log of the observed variance is a linear function of the log of the theoretical variance for a binomial distribution over the range of incidence values, and the estimated scale (?) and slope (b) parame...

There is concern that gins located in boll weevil, Anthonomus grandis grandis Boheman, eradication zones may become points of reintroduction when they process cotton grown in a neighboring infested area. We estimated boll weevil survival through two typical machine sequences used in commercial cotton gins to clean and dry the seed cotton in advance of the gin stand, as well as separately throug...

The predominant K+ channel in human T lymphocytes is Kv1.3, which inactivates by a C-type mechanism. To study assembly of these tetrameric channels in Jurkat, a human T-lymphocyte cell line, we have characterized the formation of heterotetrameric channels between endogenous wild-type (WT) Kv1.3 subunits and heterologously expressed mutant (A413V) Kv1.3 subunits. We use a kinetic analysis of C-t...

The present paper makes use of factorial experiments to assess software complexity for negative binomial distribution inputs using a new sorting algorithm which we call shift-insertion sort (insertion sort with shifting). Copyright c © 2011 Yang’s Scientific Research Institute, LLC. All rights reserved.

GENE-counter is a complete Perl-based computational pipeline for analyzing RNA-Sequencing (RNA-Seq) data for differential gene expression. In addition to its use in studying transcriptomes of eukaryotic model organisms, GENE-counter is applicable for prokaryotes and non-model organisms without an available genome reference sequence. For alignments, GENE-counter is configured for CASHX, Bowtie, ...