An experiment was carried out to study the effect of temperature on biology, oviposition and feeding behaviour as well as host preference of Epilachna beetle, Epilachna dodecastigma (Wied.) on eight varieties of brinjal, Solanum melongena Linn. from November, 2009 to June, 2010 maintaining controlled temperatures of 15oC, 25oC and 30oC using an incubator in the Department of Entomology, BAU, My...

BACKGROUND Allergen extracts can degrade when exposed to temperatures significantly beyond the optimum storage recommendation of 4 degrees C. Many allergen extracts are mailed to their final destinations throughout the year with exposure to varied environmental conditions. OBJECTIVE To evaluate the effect of summer mailing on the in vitro and in vivo potency of timothy grass extract. METHOD...

Clarification of the origin of the BAU is one of the greatest challenges in particle physics and cosmology. If the BAU is generated before T = O(1) MeV, the light element abundances (D,He,He,Li) can be explained by the standard Big-Bang cosmology. To get the right η (which is called baryogenesis) from an initially baryon symmetric universe, the so-called Sakharov’s conditions should be satisfie...

Sublingual immunotherapy (SLIT) is an effective and well-tolerated method of treating allergic respiratory diseases associated with seasonal and perennial allergens. In contrast to the subcutaneous route, SLIT requires a much greater amount of antigen to achieve a clinical effect. Many studies have shown that SLIT involves a dose-response relationship, and therefore it is important to use a pro...

BACKGROUND AND OBJECTIVE Many patients with grass pollen allergy in Spain have concomitant sensitization to other allergens such as profilin. Since this type of sensitization is more common in Mediterranean countries than in countries where most patients were enrolled in clinical trials on GRAZAX (Phleum pratense 75,000 SQ-T/2, 800 BAU, ALK), the aim of this study was to analyze tolerability to...

The biological and economic values of coral reefs are highly vulnerable to increasing atmospheric and ocean carbon dioxide concentrations. We applied the COMBO simulation model (COral Mortality and Bleaching Output) to three major U.S. locations for shallow water reefs: South Florida, Puerto Rico, and Hawaii. We compared estimates of future coral cover from 2000 to 2100 for a "business as usual...

Transthyretin is primarily synthesized in the liver and transports thyroxine vitamin A body. The transthyretin when dissociated into monomers can misfold ultimately form amyloid fibrils. There are two types of ATTR amyloidosis: hereditary (caused by mutations TTR gene) wild-type (also referred to as senile systemic amyloidosis). Amyloid cardiomyopathy develop patients with both amyloidosis, has...

Objective: This study aims to compare a generic formulation of the drug erlotinib 150 mg tablet brand-name version validate analytical method and bioequivalence studies. Methods: Erlotinib hydrochloride tablets (test versus reference formulation) were compared in randomized, two-period crossover determine their pharmacokinetic properties healthy Iranian volunteers. 14 d passed between each trea...

The relative bioavailability of the test (generic) product 2 × 25 mg baclofen tablets, with respect to the reference product, Lioresal® 2 × 25 mg tablets (baclofen; Squibb) was determined in a single-blind, single dose, randomised, crossover study. The mean values for the variable Cmax were 737.6 ng/ml for the reference and 739.5 ng/ml for the test product. The mean values for the variable AUC ...